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计算机断层扫描血管造影术中患者的辐射生物风险。

Patient radiation biological risk in computed tomography angiography procedure.

作者信息

Alkhorayef M, Babikir E, Alrushoud A, Al-Mohammed H, Sulieman A

机构信息

Department of Radiological Sciences, College of Applied Medical Sciences, King Saud University, PO Box 10219, Riyadh 11433, Saudi Arabia.

Department of Medical Physics, Prince Sultan Military Medical City, PO Box 7897, Riyadh 11159, Saudi Arabia.

出版信息

Saudi J Biol Sci. 2017 Feb;24(2):235-240. doi: 10.1016/j.sjbs.2016.01.011. Epub 2016 Jan 12.

Abstract

Computed tomography angiography (CTA) has become the most valuable imaging modality for the diagnosis of blood vessel diseases; however, patients are exposed to high radiation doses and the probability of cancer and other biological effects is increased. The objectives of this study were to measure the patient radiation dose during a CTA procedure and to estimate the radiation dose and biological effects. The study was conducted in two radiology departments equipped with 64-slice CT machines (Aquilion) calibrated according to international protocols. A total of 152 patients underwent brain, lower limb, chest, abdomen, and pelvis examinations. The effective radiation dose was estimated using ImPACT scan software. Cancer and biological risks were estimated using the International Commission on Radiological Protection (ICRP) conversion factors. The mean patient dose value per procedure (dose length product [DLP], mGy·cm) for all examinations was 437.8 ± 166, 568.8 ± 194, 516.0 ± 228, 581.8 ± 175, and 1082.9 ± 290 for the lower limbs, pelvis, abdomen, chest, and cerebral, respectively. The lens of the eye, uterus, and ovaries received high radiation doses compared to thyroid and testis. The overall patient risk per CTA procedure ranged between 15 and 36 cancer risks per 1 million procedures. Patient risk from CTA procedures is high during neck and abdomen procedures. Special concern should be provided to the lens of the eye and thyroid during brain CTA procedures. Patient dose reduction is an important consideration; thus, staff should optimize the radiation dose during CTA procedures.

摘要

计算机断层血管造影(CTA)已成为诊断血管疾病最有价值的成像方式;然而,患者会受到高辐射剂量,患癌症及其他生物学效应的概率会增加。本研究的目的是测量CTA检查过程中患者的辐射剂量,并估算辐射剂量及生物学效应。该研究在两个配备了根据国际协议校准的64层CT机(Aquilion)的放射科进行。共有152例患者接受了脑、下肢、胸部、腹部和骨盆检查。使用ImPACT扫描软件估算有效辐射剂量。使用国际放射防护委员会(ICRP)转换因子估算癌症和生物学风险。所有检查每次检查的平均患者剂量值(剂量长度乘积[DLP],mGy·cm),下肢、骨盆、腹部、胸部和脑部检查分别为437.8±166、568.8±194、516.0±228、581.8±175和1082.9±290。与甲状腺和睾丸相比,眼睛晶状体、子宫和卵巢接受的辐射剂量较高。每次CTA检查的总体患者风险为每100万次检查有15至36例癌症风险。颈部和腹部检查期间CTA检查的患者风险较高。脑部CTA检查期间应特别关注眼睛晶状体和甲状腺。降低患者剂量是一个重要的考虑因素;因此,工作人员应在CTA检查过程中优化辐射剂量。

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