精神分裂症的临床变量和血小板 Mao。
Clinical variables and platelet mao in schizophrenia.
机构信息
Reader in Bio-Psychiatry, Institute of Medical Science Banaras Hindu University, Varanasi-221 005.
出版信息
Indian J Psychiatry. 1991 Oct;33(4):271-80.
Platelet MAO activity was estimated in 60 male drug free schizophrenics and 26 controls matched for age. The paranoid group had significantly lower enzyme activity than the non-paranoid group and controls. Patients with premorbid schizoid personality had significantly lower enzyme activity than patients with non-schizoid premorbid personality and controls. A significant negative correlation between platelet MAO activity and severity and duration of illness was observed. Family history of schizophrenia, presence of auditory hallucinations and type and age of onset of illness were not related to platelet MAO activity.
对 60 名无药物治疗的男性精神分裂症患者和 26 名年龄匹配的对照组进行了血小板 MAO 活性评估。偏执组的酶活性明显低于非偏执组和对照组。有前驱期分裂型人格障碍的患者的酶活性明显低于无前驱期分裂型人格障碍的患者和对照组。血小板 MAO 活性与疾病的严重程度和持续时间呈显著负相关。精神分裂症家族史、幻听的存在以及疾病的类型和发病年龄与血小板 MAO 活性无关。
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