Edipidis K
Hygeia Medical Center, Athens, Greece.
Hippokratia. 2011 Jan;15(Suppl 1):8-12.
Women with renal disease who conceive and continue pregnancy, are at significant risk for adverse maternal and fetal outcomes. Although advances in antenatal and neonatal care continue to improve these outcomes, the risks remain proportionate to the degree of underlying renal dysfunction.The aim of this article, is to examine the impact of varying degrees of renal insufficiency on pregnancy outcome, in women with chronic renal disease and to provide if possible, useful conclusions whether and when, a woman with Chronic Kidney Disease (CKD), should decide to get pregnant.This article, reviews briefly the normal physiological changes of renal function during pregnancy, and make an attempt to clarify the nature and severity of the risks, in the settings of chronic renal insufficiency and end stage renal disease, including dialysis patients and transplant recipients.
患有肾脏疾病且怀孕并继续妊娠的女性，面临着孕产妇和胎儿不良结局的重大风险。尽管产前和新生儿护理方面的进展不断改善这些结局，但风险仍与潜在肾功能障碍的程度成正比。本文的目的是研究不同程度的肾功能不全对慢性肾病女性妊娠结局的影响，并尽可能得出关于慢性肾病（CKD）女性是否以及何时应决定怀孕的有用结论。本文简要回顾了孕期肾功能的正常生理变化，并试图阐明慢性肾功能不全和终末期肾病（包括透析患者和移植受者）情况下风险的性质和严重程度。
