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医疗沟通缺陷的风险:会阴化脓性汗腺炎引发的致命性被忽视鳞状细胞癌

The perils of a defective medical communication: fatal neglected squamous cell carcinoma arising in perineal hidradenitis suppurativa.

作者信息

Pagliarello Calogero, Paradisi Andrea

机构信息

Health Services Research Unit, IDI-IRCCS, Catholic University of the Sacred Heart, Rome, Italy.

出版信息

Case Rep Dermatol. 2011 Jan;3(1):5-7. doi: 10.1159/000323863. Epub 2011 Jan 7.

DOI:10.1159/000323863
PMID:21897818
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3155694/
Abstract

Hidradenitis suppurativa (HS) is a recurrent suppurative disease characterized by inflammatory nodules, abscesses, fistulas, and scarring. We report a case of squamous cell carcinoma arising in chronic HS. In our case the asymptomatic lesion was neglected by the patient for a long time, allowing the occurrence of advanced disease before treatment was sought, which resulted in a terminal outcome. In the context of HS, a painful lump or ulcer could easily be mistaken for an inflammatory lesion, and therefore a low threshold for biopsy is warranted.

摘要

化脓性汗腺炎(HS)是一种复发性化脓性疾病,其特征为炎性结节、脓肿、瘘管和瘢痕形成。我们报告一例慢性HS患者发生鳞状细胞癌的病例。在我们的病例中,患者长期忽视了无症状病变,导致在寻求治疗之前疾病进展至晚期,最终导致了死亡结局。在HS的背景下,疼痛性肿块或溃疡很容易被误诊为炎性病变,因此活检的阈值应较低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7de/3155694/bd1e9693a202/cde0003-0005-f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7de/3155694/bd1e9693a202/cde0003-0005-f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b7de/3155694/bd1e9693a202/cde0003-0005-f01.jpg

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本文引用的文献

1
[Fatal epidermoid carcinoma in hidradenitis suppurativa following treatment with infliximab].[英夫利昔单抗治疗后化脓性汗腺炎并发致命性表皮样癌]
Ann Dermatol Venereol. 2006 May;133(5 Pt 1):473-4. doi: 10.1016/s0151-9638(06)77566-4.
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Hidradenitis suppurativa.化脓性汗腺炎
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Hidradenitis suppurativa and squamous cell carcinoma.化脓性汗腺炎与鳞状细胞癌。
化脓性汗腺炎的最新进展:连接各个病灶
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Acne inversa (Hidradenitis suppurativa): A review with a focus on pathogenesis and treatment.化脓性汗腺炎:一篇聚焦于发病机制与治疗的综述
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Dermatol Surg. 2002 Jan;28(1):88-90. doi: 10.1046/j.1524-4725.2002.01090.x.
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Prognostic factors for local recurrence, metastasis, and survival rates in squamous cell carcinoma of the skin, ear, and lip. Implications for treatment modality selection.皮肤、耳部和唇部鳞状细胞癌局部复发、转移及生存率的预后因素。对治疗方式选择的意义。
J Am Acad Dermatol. 1992 Jun;26(6):976-90. doi: 10.1016/0190-9622(92)70144-5.