Jennings K J, MacDonald D G
Department of Prosthodontics, Glasgow Dental Hospital and School, UK.
J Dent. 1990 Apr;18(2):102-6. doi: 10.1016/0300-5712(90)90093-t.
Biopsy specimens of palatal mucosa from 10 edentulous female subjects exhibiting the signs of chronic atrophic denture-induced stomatitis were fixed and processed to produce sections which were quantitatively analysed by light microscopy. The type and degree of surface keratinization, the epithelial thickness and basement membrane morphology were assessed. Microbiological and haematological evaluations were related to the histological findings. It was found that within this clinical entity of palatal inflammation there was considerable variation in tissue response at a cellular level, and that the numbers of organisms associated with the inflammatory reaction appeared to be fewer in patients with abnormal haematological status.
对10名无牙女性受试者的腭黏膜活检标本进行固定和处理，制成切片，然后通过光学显微镜进行定量分析。这些受试者均表现出慢性萎缩性义齿性口炎的症状。评估了表面角化的类型和程度、上皮厚度以及基底膜形态。微生物学和血液学评估与组织学结果相关。研究发现，在腭部炎症这一临床实体中，细胞水平的组织反应存在相当大的差异，而且血液学状态异常的患者中，与炎症反应相关的微生物数量似乎较少。
