Department of Postgraduate and Research in Chemistry, R. D. University of Jabalpur, Jabalpur - 482001, M.P., India.
Nat Prod Res. 2011 Oct;25(18):1687-94. doi: 10.1080/14786419.2011.561205. Epub 2011 Sep 8.
Two novel triterpenoid glycosides have been isolated from butanolic seeds extract of two varieties of Lathyrus plants, i.e. Lathyrus ratan and Lathyrus aphaca. Their structures were elucidated as 3-O-[β-D-glucuronopyranosyl-(1 → 4)-α-L-arabinopyranosyl-(1 → 2)-α-L-arabinopyranosyl]-olean-11,13(18)-dien-28-oic acid (1) and 3-O-{β-D-xylopyranosyl-(1 → 2)-β-D-glcopyranosyl-(1 → 4)-[β-D-glucopyranosyl-(1 → 2)]-β-D-xylopyranosyl}-2,16α-dihydroxy-4-hydroxymethyl urs-12-en-28-oic acid (2) on the basis of spectral evidences, i.e. FTIR, (1)H-NMR, (13)C-NMR, ESI-MS and FAB-MS data. The isolated saponins were tested for their antifungal activity. Compound 1 showed maximum inhibition against Colletotrichum dematium (77.8%), whereas compound 2 showed maximum inhibition against Alternaria alternata (53.9%).
从两种雀麦植物（Lathyrus ratan 和 Lathyrus aphaca）的正丁醇种子提取物中分离得到两种新的三萜糖苷。它们的结构被阐明为 3-O-[β-D-吡喃葡萄糖醛酸基-(1 → 4)-α-L-阿拉伯吡喃糖基-(1 → 2)-α-L-阿拉伯吡喃糖基]-齐墩果酸 11,13(18)-二烯-28-酸（1）和 3-O-{β-D-吡喃木糖基-(1 → 2)-β-D-吡喃葡萄糖基-(1 → 4)-[β-D-吡喃葡萄糖基-(1 → 2)]-β-D-吡喃木糖基}-2,16α-二羟基-4-羟甲基熊-12-烯-28-酸（2）。基于光谱证据，即 FTIR、（1）H-NMR、（13）C-NMR、ESI-MS 和 FAB-MS 数据。对分离得到的皂苷进行了抗真菌活性测试。化合物 1 对炭疽菌（Colletotrichum dematium）的抑制作用最大（77.8%），而化合物 2 对交链孢菌（Alternaria alternata）的抑制作用最大（53.9%）。
