Department of Nutrition, Food Science, Physiology and Toxicology, University of Navarra, C/Irunlarrea 1, 31008 Pamplona, Spain.
Br J Nutr. 2012 Apr;107(8):1119-27. doi: 10.1017/S0007114511004235. Epub 2011 Sep 7.
The aim of the present cross-sectional study was to assess the potential relationships between fruit and vegetable (FV) consumption and some oxidative stress markers in young adults, with particular emphasis on fibre and vitamin C intake. The study enrolled 246 healthy subjects (eighty-eight men and 158 women), with a mean age of 22 (sd 3) years and a mean BMI of 21·9 (sd 2·8) kg/m2. Dietary intake, anthropometry, blood pressure, lifestyle features and blood biochemical data were assessed with validated procedures. Those subjects in the highest tertile (T) of FV consumption ( ≥ 705 g/d) had statistically lower oxidised LDL (ox-LDL) concentrations as well as higher plasma total antioxidant capacity (TAC) and glutathione peroxidase (GPx) activity (P for trend <0·05), after adjusting for sex, age, energy intake, physical activity, smoking, BMI, vitamin supplement use and other confounding factors. Moreover, plasma ox-LDL concentrations showed a decreasing trend and TAC an increasing trend across tertiles of fibre (T3: ≥14 g/d) and vitamin C (T3: ≥150 mg/d) from FV intake, while GPx activity was positively associated with vitamin C intake (P for trend < 0·05). In conclusion, greater FV consumption was independently associated with reduced ox-LDL as well as increased TAC and GPx activity in healthy young adults, with dietary fibre and vitamin C from FV clearly being implicated in this beneficial relationship.
本横断面研究旨在评估年轻人的水果和蔬菜（FV）消费与一些氧化应激标志物之间的潜在关系，特别强调膳食纤维和维生素 C 的摄入量。该研究纳入了 246 名健康受试者（88 名男性和 158 名女性），平均年龄为 22 岁（标准差 3 岁），平均 BMI 为 21.9（标准差 2.8）kg/m2。采用经过验证的程序评估饮食摄入、人体测量、血压、生活方式特征和血液生化数据。在 FV 摄入量最高的 tertile（T）（≥705 g/d）中，氧化型 LDL（ox-LDL）浓度较低，血浆总抗氧化能力（TAC）和谷胱甘肽过氧化物酶（GPx）活性较高（趋势 P < 0.05），调整性别、年龄、能量摄入、体力活动、吸烟、BMI、维生素补充剂使用和其他混杂因素后。此外，血浆 ox-LDL 浓度随 FV 膳食纤维（T3：≥14 g/d）和维生素 C（T3：≥150 mg/d）摄入量 tertile 的增加而呈下降趋势，TAC 呈上升趋势，而 GPx 活性与维生素 C 摄入量呈正相关（趋势 P < 0.05）。总之，更多的 FV 消费与健康年轻成年人 ox-LDL 降低以及 TAC 和 GPx 活性增加独立相关，来自 FV 的膳食纤维和维生素 C 显然与这种有益关系有关。
