Colorado State University, Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Fort Collins, CO 80523-1644, USA.
Vet Pathol. 2012 Sep;49(5):771-4. doi: 10.1177/0300985811419531. Epub 2011 Sep 7.
Lymphoma in the left femoral nerve of a 10-year-old English Cocker Spaniel caused complete paralysis of the affected limb. Neoplastic cells were immunopositive for CD79a and Pax5 and negative for CD3. Neoplastic cells were in multiple lymph nodes and one kidney but spared bone marrow. The clinical and histologic features in this case resemble those of the rare human condition of neurolymphomatosis.
一只 10 岁的英国可卡犬的左腿股神经中发生淋巴瘤，导致受影响的肢体完全瘫痪。肿瘤细胞免疫阳性表达 CD79a 和 Pax5，而阴性表达 CD3。肿瘤细胞存在于多个淋巴结和一个肾脏中，但骨髓未受累及。本例的临床和组织学特征类似于罕见的人类神经淋巴瘤病。
