d'Agay M F, Ter-Mimasian D, Trédaniel J, Oksenhendler E, Brocheriou C
Laboratoire d'Anatomie Pathologique, Hôpital Saint-Louis, Paris, France.
Nouv Rev Fr Hematol (1978). 1990;32(1):107-8.
Histiocytic necrotizing lymphadenitis (HNL) or Kikuchi's Disease is a peculiar condition most commonly affecting cervical lymph nodes in young women. Histology and immunohistochemistry demonstrate a florid T-cell and histiocytic reaction associated with necrotic areas which must be carefully distinguished from malignant lymphoma. Usually, the disease resolves spontaneously within a few weeks or months. The etiology is unknown and the physiopathology discussed.