Department of Clinical Nutrition and Dietetics, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Nutrition. 2011 Oct;27(10):1002-7. doi: 10.1016/j.nut.2010.11.004.
Several studies have shown that dietary and plasma fatty acid (FA) composition can modulate the development of metabolic syndrome, but epidemiologic data are scarce. The aim of this study was to evaluate the association between dietary FA composition and metabolic syndrome in Tehranian adults.
Dietary FA composition and symptoms of metabolic syndrome were assessed in a population-based cross-sectional study of 822 participants (354 men and 468 women, 18-74 y old) as part of the Tehran Lipid and Glucose Study. Metabolic syndrome was defined according to the guidelines presented by the Adult Treatment Panel III.
The means ± standard deviations for dietary FA composition of total fat, linoleic acid, oleic acid, and saturated FA were 30.3 ± 7.5%, 1.43 ± 1.76%, 2.87 ± 2.19%, and 5.7 ± 2.2% of daily consumed energy, respectively. No significant correlation between the percentage of linoleic or oleic acids and metabolic syndrome was observed. Participants whose consumption of saturated FA was in the highest quartile had a significantly increased probability of acquiring metabolic syndrome (odds ratios by quartile 1, 0.83, 0.91, 0.95, P for trend <0.03). The odds ratios decreased after adjusting for indicators of a healthy lifestyle, including diet.
The data from this study indicate that increased consumption of dietary total fat, especially saturated FA, is associated with a higher risk of metabolic syndrome in Tehranian adults. The relation, apparently, is influenced by an individual's lifestyle.
多项研究表明，饮食和血浆脂肪酸（FA）组成可以调节代谢综合征的发展，但流行病学数据有限。本研究旨在评估德黑兰成年人饮食 FA 组成与代谢综合征之间的关系。
在一项基于人群的横断面研究中，评估了 822 名参与者（354 名男性和 468 名女性，年龄 18-74 岁）的饮食 FA 组成和代谢综合征症状，这是德黑兰血脂和血糖研究的一部分。代谢综合征根据成人治疗小组 III 提出的指南定义。
总脂肪、亚油酸、油酸和饱和 FA 的饮食 FA 组成的平均值±标准偏差分别为每日摄入能量的 30.3±7.5%、1.43±1.76%、2.87±2.19%和 5.7±2.2%。亚油酸或油酸的百分比与代谢综合征之间没有显著相关性。饱和 FA 摄入量最高的 quartile 组发生代谢综合征的可能性显著增加（四分位数 1、0.83、0.91、0.95 的比值比，趋势 P<0.03）。调整健康生活方式的指标（包括饮食）后，比值比下降。
本研究数据表明，德黑兰成年人饮食总脂肪（尤其是饱和 FA）的增加与代谢综合征的风险增加相关。这种关系显然受到个人生活方式的影响。
