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经尿道前列腺切除术治疗良性前列腺增生:随机前瞻性研究

Influence of bladder neck suspension stitches on early continence after radical prostatectomy: a prospective randomized study of 180 patients.

机构信息

Department of Urology, University of Leipzig, Leipzig 04103, Germany.

出版信息

Asian J Androl. 2011 Nov;13(6):806-11. doi: 10.1038/aja.2011.82. Epub 2011 Sep 12.

Abstract

Several techniques have been introduced to improve early postoperative continence. In this study, we evaluated the impact of bladder neck (vesicourethral anastomosis) suspension on the outcome of extraperitoneal endoscopic radical prostatectomy (EERPE). In this research, a total of 180 patients underwent EERPE. Group 1 included patients who underwent nerve-sparing EERPE (nsEERPE) (n=45), and Group 2 included patients who underwent nsEERPE with bladder neck suspension (BNS, n=45). Groups 3 (n=45) and 4 (n=45) included patients who received EERPE and EERPE with BNS, respectively. Patients were randomly assigned to receive BNS with their nsEERPE or EERPE procedure. Perioperative parameters were recorded, and continence was evaluated by determining the number and weight of absorbent pads (pad weighing test) on the second day after catheter removal and by a questionnaire 3 months postoperatively. Two days after catheter removal, 11.1% of Group 1, 11.1% of Group 2, 4.4% of Group 3 and 8.9% of Group 4 were continent. The average urine loss was 80.4, 70.1, 325.0 and 291.3 g for the each of these groups, respectively. At 3 months, 76.5% of Group 1 and 81.3% of Group 2 were continent. The continence figures for Group 3 and 4 were 48.5% and 43.8%, respectively. Similar overall rates were observed in all groups. In conclusion, although there are controversial reports in the literature, early continence was never observed to be significantly higher in the BNS groups when compared with the non-BNS groups, regardless of the EERPE technique performed.

摘要

已经引入了几种技术来改善早期术后的控尿能力。在这项研究中,我们评估了膀胱颈部(膀胱尿道吻合术)悬吊术对腹膜外内镜前列腺根治术(EERPE)结果的影响。在这项研究中,共有 180 名患者接受了 EERPE。第 1 组包括接受神经保留 EERPE(nsEERPE)的患者(n=45),第 2 组包括接受 nsEERPE 联合膀胱颈部悬吊术(BNS)的患者(n=45)。第 3 组(n=45)和第 4 组(n=45)分别包括接受 EERPE 和 EERPE 联合 BNS 的患者。患者被随机分配接受 BNS 联合 nsEERPE 或 EERPE 手术。记录围手术期参数,并通过在导管拔除后第二天确定吸收垫的数量和重量(垫称重试验)以及术后 3 个月的问卷调查来评估控尿能力。导管拔除后第 2 天,第 1 组的 11.1%、第 2 组的 11.1%、第 3 组的 4.4%和第 4 组的 8.9%的患者是控尿的。这些组的平均尿失量分别为 80.4、70.1、325.0 和 291.3g。术后 3 个月,第 1 组的 76.5%和第 2 组的 81.3%的患者是控尿的。第 3 组和第 4 组的控尿率分别为 48.5%和 43.8%。所有组的总体率相似。总之,无论采用何种 EERPE 技术,与非 BNS 组相比,BNS 组的早期控尿能力从未显著更高,尽管文献中有争议的报道。

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