Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), School of Chemistry & Chemical Engineering of Guangxi Normal University, Guilin 541004, People's Republic of China.
J Org Chem. 2011 Oct 21;76(20):8472-6. doi: 10.1021/jo201010d. Epub 2011 Sep 26.
A novel indium(III)-catalyzed cyclotrimerization of alkynes in the presence of 2-iodophenol gave 1,3,5-substituted benzenes in excellent yields with complete regioselectivity. The reaction condition is tolerant to air, and atom economical, in accordance with the concept of modern green chemistry. This method provides a rapid and efficient access to 1,3,5-substituted benzenes.
一种新型的铟(III)催化炔烃环三聚反应，在 2-碘苯酚的存在下，以优异的收率和完全的区域选择性得到 1,3,5-取代苯。该反应条件对空气具有耐受性，符合原子经济性，符合现代绿色化学的理念。该方法为 1,3,5-取代苯的快速高效合成提供了一种新途径。
