Section of Endocrinology, Andrology and Internal Medicine and Master in Andrological, Human Reproduction and Biotechnology Sciences, Department of Internal Medicine and Systemic Diseases, Catania University, Catania, Italy.
Andrologia. 2012 May;44 Suppl 1:26-31. doi: 10.1111/j.1439-0272.2010.01132.x. Epub 2011 Sep 15.
MAGI is the inflammation of the accessory male glands that notoriously exerts a negative influence on male fertility. The diagnosis is integrated by clinical, laboratory and ultrasound evaluation. In particular, the ultrasound criteria were published in 1999. The aim of this study was to analyse the sensitivity and specificity of additional diagnostic ultrasound criteria as well as of conventional criteria in a selected category of infertile patients with MAGI. To accomplish this, 100 patients with MAGI were evaluated by scrotal and transrectal ultrasound by three different operators. The control group consisted of 100 age-matched healthy men. Statistical analysis was performed to evaluate sensitivity, specificity, positive and negative predictive values, and ROC curve analysis. The results showed that additional ultrasound criteria had a diagnostic accuracy similar to traditional criteria. The threshold value of two criteria for each diagnostic category (traditional and additional criteria) obtained high values of sensitivity and specificity. In conclusion, this study confirms the validity of the ultrasound criteria of MAGI previously published; in addition, it suggests the clinical utility of other indicators in clinical practice with good diagnostic accuracy and finally it establishes a clear threshold ultrasonographic value for the diagnosis of MAGI.
MAGI 是附属男性腺体的炎症，它对男性生育力有负面影响，这是众所周知的。诊断包括临床、实验室和超声评估。特别是，超声标准于 1999 年公布。本研究的目的是分析在 MAGI 特定类别不育患者中，附加诊断超声标准以及常规标准的敏感性和特异性。为此，通过三位不同的操作者对 100 例 MAGI 患者进行了阴囊和经直肠超声检查。对照组由 100 名年龄匹配的健康男性组成。进行了统计分析，以评估敏感性、特异性、阳性和阴性预测值以及 ROC 曲线分析。结果表明，附加超声标准与传统标准具有相似的诊断准确性。每个诊断类别（传统和附加标准）的两个标准的阈值值获得了高的敏感性和特异性。总之，这项研究证实了先前发表的 MAGI 超声标准的有效性；此外，它还表明了在临床实践中使用其他指标的临床实用性，这些指标具有良好的诊断准确性，最终为 MAGI 的诊断建立了明确的超声阈值值。
