Kennedy Krieger Institute, and Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Brain. 2012 Mar;135(Pt 3):656-77. doi: 10.1093/brain/awr210. Epub 2011 Sep 15.
Distortions in time perception and timed performance are presented by a number of different neurological and psychiatric conditions (e.g. Parkinson's disease, schizophrenia, attention deficit hyperactivity disorder and autism). As a consequence, the primary focus of this review is on factors that define or produce systematic changes in the attention, clock, memory and decision stages of temporal processing as originally defined by Scalar Expectancy Theory. These findings are used to evaluate the Striatal Beat Frequency Theory, which is a neurobiological model of interval timing based upon the coincidence detection of oscillatory processes in corticostriatal circuits that can be mapped onto the stages of information processing proposed by Scalar Timing Theory.
许多不同的神经和精神疾病都会导致时间感知和定时表现的扭曲（例如帕金森病、精神分裂症、注意力缺陷多动障碍和自闭症）。因此，本综述的主要重点是定义或产生时间处理的注意、时钟、记忆和决策阶段的系统变化的因素，这些变化最初是由标量预期理论定义的。这些发现用于评估纹状体拍频理论，这是一种基于皮质纹状体回路中振荡过程的吻合检测的神经生物学间隔计时模型，可以映射到标量定时理论提出的信息处理阶段。
