Centre for Prevention and Health Services Research, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.
Obes Facts. 2011;4(4):264-9. doi: 10.1159/000331015. Epub 2011 Aug 13.
This study prospectively assessed the association between body mass index (BMI) and cognitive ability of young children, while accounting for confounding factors.
The study included 236 children born between 1990 and 1994 participating in a Dutch birth cohort study. Anthropometric data of the children at birth, 4, and 7 years of age were collected from growth records or measured at the Academic Hospital of Maastricht. The Kaufman Assessment Battery for Children (K-ABC) was used to assess cognitive ability at 7 years of age. The association between BMI and cognitive ability was investigated using univariate and multivariate linear regression analyses, including various covariates.
Although the results suggest that cognitive ability at 7 years of age decreased with increasing BMI at 4 years and 7 years of age, this association was not significant in any performed analysis. Multivariate analyses showed that maternal intelligence was strongly associated with all scales of the K-ABC as a significant covariate. Adjusting analyses for physical fitness of the child, maternal education, maternal pre-pregnancy BMI, maternal smoking during pregnancy, and birth weight did not change the results.
This study found no evidence for an association between BMI and cognitive ability of school-aged children.
本研究前瞻性评估了儿童期 BMI 与认知能力之间的关系,同时考虑了混杂因素。
本研究纳入了 1990 年至 1994 年期间出生的 236 名儿童,他们参加了一项荷兰出生队列研究。从生长记录中收集了儿童在出生、4 岁和 7 岁时的人体测量数据,或在马斯特里赫特学术医院进行测量。使用 Kaufman 儿童评估成套测验(K-ABC)评估 7 岁时的认知能力。使用单变量和多变量线性回归分析,包括各种协变量,研究了 BMI 与认知能力之间的关系。
尽管结果表明认知能力在 7 岁时随 4 岁和 7 岁时 BMI 的增加而降低,但在任何进行的分析中,这种关联均不显著。多变量分析表明,母亲的智力是 K-ABC 所有量表的一个重要协变量,与所有量表均显著相关。对儿童的身体状况、母亲的教育程度、母亲怀孕前的 BMI、母亲怀孕期间吸烟和出生体重进行调整分析,并未改变结果。
本研究未发现 BMI 与学龄儿童认知能力之间存在关联的证据。