π-π 堆积作用和羧酸碳纳米粒子与荧光寡核苷酸之间的静电排斥作用的结合用于快速灵敏地检测凝血酶。
Combination of π-π stacking and electrostatic repulsion between carboxylic carbon nanoparticles and fluorescent oligonucleotides for rapid and sensitive detection of thrombin.
机构信息
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, China.
出版信息
Chem Commun (Camb). 2011 Oct 28;47(40):11321-3. doi: 10.1039/c1cc14445f. Epub 2011 Sep 15.
PMID:21922082
Abstract
On the basis of simultaneous electrostatic repulsion and π-π stacking interactions of carboxylic carbon nanoparticles (cCNPs) with single-stranded DNA, a noncovalent assembly of cCNPs and fluorescent aptamers is reported for rapid, sensitive, and selective detection of thrombin.
摘要
基于羧酸碳纳米粒子（cCNPs）与单链 DNA 之间的静电排斥和π-π堆积相互作用，报告了 cCNPs 和荧光适体的非共价组装，用于快速、灵敏和选择性检测凝血酶。
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