Department of Neurology, Hospital Español, Belgrano 2975, C1209AAB Buenos Aires, Argentina.
Rheumatol Int. 2012 Dec;32(12):4061-3. doi: 10.1007/s00296-011-2130-5. Epub 2011 Sep 16.
A patient with chronic inflammatory demyelinating polyradiculoneuropathy and systemic lupus erythematosus arising after rubella vaccination was initially treated with plasmapheresis, corticosteroids and intravenous immunoglobulins, with partial response. After shift to rituximab, most clinical symptoms improved markedly, emphasizing the possible role of this monoclonal antibody in conventional therapy-resistant cases.
一名慢性炎症性脱髓鞘性多发性神经病和系统性红斑狼疮患者在接种风疹疫苗后发病,最初接受了血浆置换、皮质类固醇和静脉注射免疫球蛋白治疗,部分缓解。改用利妥昔单抗后,大多数临床症状明显改善,这强调了这种单克隆抗体在常规治疗抵抗病例中的可能作用。