来自抱茎小苦荬的两种新倍半萜内酯。

Two new sesquiterpene lactones from Ixeris sonchifolia.

作者信息

Song Shao-jiang, Zhou Ling-yan, Li Ling-zhi, Gao Pin-yi, Jia Wei-wei, Peng Ying

机构信息

School of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, P.R. China.

出版信息

Nat Prod Commun. 2011 Aug;6(8):1055-7.

PMID:21922897

Abstract

The structures of two new sesquiterpene lactones, 11,13beta-dihydroixerin Z (1) and Ixerin Z2 (2) isolated from Ixeris sonchifolia were determined to be 3-hydroxy-1(10),3-guaiadiene-12,6-olide-2-one-3-O-beta-D-glucopyranoside and 1(10),3,11 (13)-guaiatriene-12,6-olide-2-one-3-O-[6'-(4"-hydroxybenzyl lactyl)]-beta-D-glucopyranoside, respectively on the basis of detailed spectral analysis.

摘要

从抱茎小苦荬中分离得到的两种新倍半萜内酯，11,13β - 二氢苦荬菜内酯Z（1）和苦荬菜内酯Z2（2），经详细光谱分析确定其结构分别为3 - 羟基 - 1(10),3 - 愈创木二烯 - 12,6 - 内酯 - 2 - 酮 - 3 - O - β - D - 吡喃葡萄糖苷和1(10),3,11 (13) - 愈创木三烯 - 12,6 - 内酯 - 2 - 酮 - 3 - O - [6' - (4" - 羟基苄基乳酰基)] - β - D - 吡喃葡萄糖苷。