缺乏病毒核衣壳的非感染性水泡性口炎病毒颗粒。
Noninfectious vesicular stomatitis virus particles deficient in the viral nucleocapsid.
作者信息
Schnitzer T J, Lodish H F
出版信息
J Virol. 1979 Feb;29(2):443-7. doi: 10.1128/JVI.29.2.443-447.1979.
Abstract
Several temperature-sensitive mutants of vesicular stomatitis virus in complementation group III produce, at nonpermissive temperature, noninfectious particles which contain the viral M (matrix) and G (glycoprotein) proteins but less than 10% of the normal proportion of N protein or RNA. Since group III mutants are thought to be defective in the structural gene for the virus M protein, these findings demonstrate that an interaction between M and the nucleocapsid is of importance in virus budding. Taken together with earlier results, they suggest that M is the key protein in bud formation.
摘要
水泡性口炎病毒互补群III中的几个温度敏感突变体在非允许温度下产生非感染性颗粒，这些颗粒含有病毒的M（基质）蛋白和G（糖蛋白），但N蛋白或RNA的含量不到正常比例的10%。由于认为III组突变体在病毒M蛋白的结构基因上存在缺陷，这些发现表明M与核衣壳之间的相互作用在病毒出芽过程中很重要。结合早期结果，这些发现提示M是出芽形成中的关键蛋白。
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1
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Nature. 1970 Aug 15;227(5259):680-5. doi: 10.1038/227680a0.
2
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J Virol. 1974 Nov;14(5):1220-8. doi: 10.1128/JVI.14.5.1220-1228.1974.
3
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