Arkansas Biosciences Institute, Arkansas State University, Jonesboro, AR 72401, United States.
Biotechnol Adv. 2012 Sep-Oct;30(5):1171-84. doi: 10.1016/j.biotechadv.2011.08.020. Epub 2011 Sep 8.
Molecular farming, long considered a promising strategy to produce valuable recombinant proteins not only for human and veterinary medicine, but also for agriculture and industry, now has some commercially available products. Various plant-based production platforms including whole-plants, aquatic plants, plant cell suspensions, and plant tissues (hairy roots) have been compared in terms of their advantages and limits. Effective recombinant strategies are summarized along with descriptions of scalable culture systems and examples of commercial progress and success.
分子农业长期以来被认为是一种很有前途的策略，不仅可以生产用于人类和兽医医学的有价值的重组蛋白，还可以用于农业和工业。现在已经有一些商业化的产品。各种基于植物的生产平台，包括整株植物、水生植物、植物细胞悬浮液和植物组织（发根），已经在其优势和限制方面进行了比较。本文总结了有效的重组策略，描述了可扩展的培养系统，并举例说明了商业进展和成功。
