糖尿病视网膜病变的患病率及危险因素：一项伊朗眼部研究。

Prevalence and risk factors for diabetic retinopathy: an Iranian eye study.

作者信息

Heydari Behrouz, Yaghoubi Gholamhossein, Yaghoubi Mohammad Ali, Miri Mohammad Reza

机构信息

Department of Ophthalmology, Birjand University of Medical Sciences, Birjand, Iran.

出版信息

Eur J Ophthalmol. 2012 May-Jun;22(3):393-7. doi: 10.5301/ejo.5000044.

DOI:10.5301/ejo.5000044

PMID:21928255

Abstract

PURPOSE

The aim of this study was to determine the prevalence of diabetic retinopathy among diabetic patients in Iran and its association with some predisposing factors.

METHODS

All diabetic patients who attended the diabetes clinic underwent ocular examination, including slit-lamp biomicroscopy. The blood pressure and blood biochemical parameters were then measured.

RESULTS

The prevalence of diabetic retinopathy among 1022 diabetic participants was 23.6% (241 cases). This study showed that there is a statistically significant relation between diabetic retinopathy and mean blood pressure, fasting blood sugar, blood urea nitrogen, and level of HbA1c. There was no difference in lipid profile between patients with and without retinopathy. The duration of diabetes was a predicting factor for retinopathy as well as presence of renal and cardiovascular diseases and fasting glucose >126 as independent variables.

CONCLUSIONS

The duration of diabetes was the most important risk factor for progression of retinopathy.

摘要

目的

本研究旨在确定伊朗糖尿病患者中糖尿病视网膜病变的患病率及其与一些易感因素的关联。

方法

所有前往糖尿病门诊就诊的糖尿病患者均接受了眼科检查，包括裂隙灯生物显微镜检查。随后测量血压和血液生化参数。

结果

1022名糖尿病参与者中糖尿病视网膜病变的患病率为23.6%（241例）。本研究表明，糖尿病视网膜病变与平均血压、空腹血糖、血尿素氮和糖化血红蛋白水平之间存在统计学上的显著关系。有视网膜病变和无视网膜病变的患者之间血脂水平无差异。糖尿病病程是视网膜病变的预测因素，同时肾脏和心血管疾病的存在以及空腹血糖>126作为自变量。