埃及亚历山大和北西三角洲地区糖尿病患者糖尿病视网膜病变的患病率。
Prevalence of diabetic retinopathy in patients with diabetes in Alexandria and North-West Delta, Egypt.
机构信息
Ophthalmology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Computer Systems and Engineering Department, Faculty of Engineering, Alexandria University, Alexandria, Egypt.
出版信息
Int Ophthalmol. 2023 Aug;43(8):2883-2895. doi: 10.1007/s10792-023-02692-4. Epub 2023 Mar 24.
PURPOSE
The purpose of this research was to estimate the prevalence of DR in Alexandria and the North-West Delta region.
METHODS
All diabetic patients attending the general ophthalmology clinics (Group 1), diabetic internal medicine clinics (Group 2), or reached out in the local communities (Group 3) were eligible to participate. Fundus photographs were graded according to the Scottish DR grading system by three independent UK-certified graders. Adjudication by a consultant was done when needed.
RESULTS
Out of 11,033 screened patients, 10,811 had a gradable fundus photograph in at least one eye and were included. The numbers of cases in groups 1, 2 and 3 were 3940, 2826, and 4045, respectively. Males represented 38.35% of the cases. Mean age was 55 ± 12.63. For the whole sample, groups 1, 2 and 3, the DR prevalence was 32.49, 46.4%, 29.13%, and 21.29%, respectively. The prevalence of proliferative DR (grade R4) was 6.16%, 11.83%, 5.02%, and 1.45%, respectively, and of referable maculopathy (Grade M2) was 19.95%, 31.42%, 15.92%, and 11.59%, respectively. In univariate analysis, older age, higher random blood glucose, and longer DM duration were associated with a higher risk of both DR and referable diabetic maculopathy. This association was maintained in multivariate analysis for the high random blood glucose level and the longer duration of DM (but not for the older age).
CONCLUSION
A significantly higher prevalence of DR, grades R4 and M2 was found in the hospital-recruited patients than in diabetics from the local communities.
目的
本研究旨在估计亚历山大和北西三角洲地区糖尿病视网膜病变（DR）的患病率。
方法
所有在普通眼科诊所（第 1 组）、糖尿病内科诊所（第 2 组）就诊或在当地社区接受检查的糖尿病患者均有资格参加。眼底照片根据苏格兰 DR 分级系统由三位独立的英国认证分级员进行分级。如有需要，由顾问进行裁决。
结果
在筛选出的 11033 名患者中，有 10811 名患者至少有一只眼睛的眼底照片可分级，包括在内。第 1、2 和 3 组的病例数分别为 3940、2826 和 4045。男性占病例的 38.35%。平均年龄为 55±12.63 岁。对于整个样本、第 1、2 和 3 组，DR 的患病率分别为 32.49%、46.4%、29.13%和 21.29%。增殖性 DR（R4 级）的患病率分别为 6.16%、11.83%、5.02%和 1.45%，可转诊的黄斑病变（M2 级）的患病率分别为 19.95%、31.42%、15.92%和 11.59%。单因素分析显示，年龄较大、随机血糖较高和糖尿病病程较长与 DR 和可转诊的糖尿病性黄斑病变的风险增加相关。这种相关性在多变量分析中仍然存在，与高随机血糖水平和较长的糖尿病病程相关（但与年龄无关）。
结论
与来自当地社区的糖尿病患者相比，在医院招募的患者中发现了更高的 DR、R4 和 M2 级患病率。
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