Shapiro L S
Albany Medical College, NY.
J Rheumatol. 1990 May;17(5):685-8.
A 69-year-old woman with systemic sclerosis developed thrombosis of each superficial femoral artery requiring above-knee amputations. On pathologic examination of the involved vessels, atherosclerotic changes were minimal and thrombus formation was the primary abnormality. The presence of antiphospholipid antibody suggested an acquired predisposition to vascular thrombosis. Prior reports of large vessel thrombosis in systemic sclerosis are reviewed.
一名69岁的系统性硬化症女性患者双侧股浅动脉发生血栓形成，需要进行膝上截肢。对受累血管进行病理检查时，发现动脉粥样硬化改变轻微，血栓形成是主要异常。抗磷脂抗体的存在提示存在获得性血管血栓形成易感性。本文回顾了系统性硬化症中关于大血管血栓形成的既往报道。
