西半球的 archazolid 的合成与活性。
Synthesis and activity of the archazolid western hemisphere.
机构信息
Department of Chemistry, Western Washington University, Bellingham, WA, USA.
出版信息
Org Biomol Chem. 2011 Oct 26;9(22):7671-4. doi: 10.1039/c1ob06446k. Epub 2011 Sep 20.
PMID:21931924
Abstract
A convergent and scalable synthesis of the archazolid western hemisphere has been completed. The V-ATPase inhibitory activity of this compound along with a previously prepared eastern domain was then tested using a convenient Arabidopsis-based V-ATPase assay.
摘要
已完成了 archazolid 西半球的一种收敛且可规模化的合成。然后使用方便的拟南芥 V-ATPase 测定法测试了该化合物以及先前制备的东部结构域的 V-ATPase 抑制活性。
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