Department of Oncologic Sciences, College of Medicine, University of South Florida, Tampa, Florida 33612, USA.
J Adolesc Health. 2011 Oct;49(4):337-46. doi: 10.1016/j.jadohealth.2011.01.005. Epub 2011 Mar 15.
The knowledge that cancer treatment may impair fertility in pediatric populations is an emerging aspect of quality of life in this population. However, decision making and use of fertility preservation (FP) among adolescent cancer patients and their families has not been well studied. This review summarizes the available published data on aspects of decision making and FP in adolescent cancer patients.
An electronic search was performed to identify peer-reviewed studies published between 1999 and 2009 using key Medical Subject Heading terms and inclusion criteria. Inclusion criteria limited eligible studies to those that focused on adolescent decision making in cancer treatment or FP, fertility concerns in pediatric oncology, capacity for decision making, and health decision making in pediatrics. Studies that did not meet at least one of these criteria were excluded.
A total of 29 articles were reviewed and summarized. Three categories of results were seen: a focus on adolescent decision making in oncology, decision making in chronic illness, and decision making in cancer-related infertility and preservation.
Most of the studies showed that adolescents have a strong desire to participate in decisions related to their cancer treatment and many have concerns regarding their future fertility, although barriers often prevented these discussions. More research is needed to explore the role of teenagers and parents in decisions about fertility in relation to cancer treatment.
癌症治疗可能损害儿科人群的生育能力，这是该人群生活质量的一个新方面。然而，青少年癌症患者及其家属的决策和使用生育力保存（FP）尚未得到充分研究。本综述总结了目前关于青少年癌症患者决策和 FP 方面的可用已发表数据。
使用主要医学主题词和纳入标准进行电子检索，以确定 1999 年至 2009 年期间发表的同行评审研究。纳入标准将符合条件的研究限于关注青少年在癌症治疗或 FP 中的决策、儿科肿瘤学中的生育问题、决策能力以及儿科保健决策的研究。不符合这些标准之一的研究被排除在外。
共审查并总结了 29 篇文章。有三个类别的结果：聚焦于肿瘤学中的青少年决策、慢性病中的决策以及癌症相关不孕不育和保存中的决策。
大多数研究表明，青少年强烈希望参与与癌症治疗相关的决策，许多人对自己未来的生育能力表示担忧，尽管这些讨论往往存在障碍。需要进一步研究来探讨青少年和家长在与癌症治疗相关的生育问题方面的决策中的作用。
