比较儿童艰难梭菌菌株与成人艰难梭菌相关性感染中流行的菌株的分子流行病学。
Molecular epidemiology of Clostridium difficile strains in children compared with that of strains circulating in adults with Clostridium difficile-associated infection.
机构信息
Nuffield Department of Clinical Medicine, Oxford University, John Radcliffe Hospital, Oxford OX3 9DU, UK.
出版信息
J Clin Microbiol. 2011 Nov;49(11):3994-6. doi: 10.1128/JCM.05349-11. Epub 2011 Sep 21.
Abstract
Molecular analysis of Clostridium difficile (28 isolates) from children (n = 128) in Oxfordshire, United Kingdom, identified eight toxigenic genotypes. Six of these were isolated from 27% of concurrent adult C. difficile-associated infections studied (n = 83). No children carried hypervirulent PCR ribotype 027. Children could participate in the transmission of some adult disease-causing genotypes.
摘要
对英国牛津郡（Oxfordshire）的 128 例儿童（n=128）中分离的 28 株艰难梭菌（Clostridium difficile）（28 株艰难梭菌）进行分子分析，鉴定出 8 种产毒基因型。其中 6 种从同时研究的 83 例成人艰难梭菌相关性感染（n=83）中的 27%中分离出来。没有儿童携带高毒力 PCR 核糖型 027。儿童可能参与了一些成人致病基因型的传播。
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