Nephrology Research and Development Unit, Department of Nephrology, Hospital São João, Faculty of Medicine, University of Porto, Portugal.
Nephrol Dial Transplant. 2012 May;27(5):1993-6. doi: 10.1093/ndt/gfr532. Epub 2011 Sep 21.
Physical examination (PE) of arteriovenous fistulae (AVF) has recently emerged as an important element in the detection of stenotic lesions. This study examines the accuracy of PE in the assessment of AVF dysfunction by non-interventionalists in comparison with angiography.
A total of 177 consecutive patients who had AVF dysfunction and were referred to our centre by general nephrologists for angioplasty between November 2009 and July 2010 were included in this analysis. Eleven referring general nephrologists completed a form reporting the PE findings regarding their patients' AVFs. Before angiography examination was carried out, a trained nephrology resident performed a PE in all the cases. Angiography of the AVFs was then performed by an interventionalist. Cohen's κ value was used as the measurement of the level of agreement beyond chance between the diagnosis made on PE and angiography.
There was a moderate agreement beyond chance between the general nephrologists' PE and angiography in the detection of AVF inflow stenosis (κ = 0.49), outflow stenosis (κ = 0.58) and thrombosis (κ = 0.52). On the other hand, PE performed by the trained nephrology resident strongly agreed with angiography in the detection of AVF inflow stenosis (κ = 0.84), outflow stenosis (κ = 0.92) and thrombosis (κ = 0.98). The agreement between PE and angiography in the detection of co-existing AVF inflow-outflow stenosis was poor for the general nephrologists and moderate for the trained nephrology resident (κ = 0.14 versus κ = 0.55, respectively).
PE may provide an accurate means of diagnosis of AVF dysfunction. Theoretical and hands-on training in PE of dysfunctional AVFs should be provided for nephrologists in-training and for the dialysis staff.
体格检查(PE)在动静脉瘘(AVF)中的应用,最近已成为检测狭窄病变的重要内容。本研究通过非介入医师对 AVF 功能障碍的评估,检验 PE 在检测 AVF 功能障碍中的准确性,并与血管造影术进行对比。
2009 年 11 月至 2010 年 7 月期间,共有 177 名因 AVF 功能障碍,而被普通肾病医师转诊至本中心接受血管成形术的患者,纳入本研究。11 名转诊的普通肾病医师完成了一份报告,内容为他们患者的 AVF 的体格检查结果。在进行血管造影检查之前,由一名受过培训的肾病住院医师对所有病例进行了体格检查。然后由介入医师对 AVF 进行血管造影。使用 Cohen κ 值来衡量体格检查和血管造影在诊断 AVF 内瘘狭窄(κ=0.49)、流出道狭窄(κ=0.58)和血栓形成(κ=0.52)方面的一致性程度。另一方面,受过培训的肾病住院医师进行的体格检查在检测 AVF 内瘘狭窄(κ=0.84)、流出道狭窄(κ=0.92)和血栓形成(κ=0.98)方面与血管造影具有高度一致性。普通肾病医师在检测同时存在的 AVF 内瘘-流出道狭窄方面的体格检查与血管造影之间的一致性较差,而受过培训的肾病住院医师的一致性则为中度(κ=0.14 与 κ=0.55)。
PE 可能是一种准确诊断 AVF 功能障碍的方法。应向肾病学受训医师和透析工作人员提供关于 AVF 功能障碍的体格检查的理论和实践培训。