FMRIB Centre, Nuffield Dept of Clinical Neurosciences, University of Oxford, Oxford, UK.
Neuroimage. 2012 Aug 15;62(2):648-51. doi: 10.1016/j.neuroimage.2011.09.010. Epub 2011 Sep 16.
The early functional MRI research programme at the National Institutes of Health, described by Robert Turner in an accompanying article in this volume, was the first to combine echo planar imaging (EPI) and high field in the pursuit of fMRI. As such, it soon became apparent that one of the obstacles to interpreting fMRI data using EPI was the presence of geometric distortions caused by static field inhomogeneities. This meant that EPI data did not properly align spatially with conventionally acquired MRI scans that showed structural information. This article describes some of the approaches that have been adopted to ensure that spatial warping caused by field inhomogeneities can be corrected so that functional and structural information can be co-aligned.
本卷中罗伯特·特纳（Robert Turner）的一篇相关文章描述了美国国立卫生研究院（National Institutes of Health）早期的功能磁共振成像（fMRI）研究计划，该计划率先将回波平面成像（EPI）和高磁场结合起来，以追求 fMRI。因此，人们很快意识到，使用 EPI 解释 fMRI 数据的一个障碍是静态磁场不均匀性引起的几何变形。这意味着 EPI 数据与显示结构信息的常规采集的 MRI 扫描在空间上无法正确对齐。本文描述了已采用的一些方法，以确保可以纠正由磁场不均匀性引起的空间扭曲，从而可以使功能和结构信息对齐。
