Department of Psychiatry, University of Pennsylvania, Philadelphia Veterans Affairs Medical Center, USA.
Am J Geriatr Psychiatry. 2011 Oct;19(10):851-8. doi: 10.1097/JGP.0b013e318202c1dc.
The purpose of this study is to explore behavioral health symptoms and characteristics of noninstitutionalized older adults newly started on an antidepressant, anxiolytic, or antipsychotic agent by nonpsychiatrist physicians.
Naturalistic cohort study of older adults participating in the Pharmaceutical Assistance Contract for the Elderly (PACE) of the state of Pennsylvania.
SETTING/PARTICIPANTS: Noninstitutionalized adults in Pennsylvania.
Standardized scales including the Blessed Orientation-Memory-Concentration (BOMC) test, Mini International Neuropsychiatric Interview (including Psychosis, Mania, Generalized Anxiety Disorder [GAD], Panic Disorder, and Alcohol Abuse/Dependence modules), Patient Health Questionnaire-9 (PHQ-9), Paykel Scale for suicide ideation, and Medical Outcomes Survey (SF-12).
Participants were mostly women (83.7%) with a mean age of 79.2 years (SD 7.1). The average PHQ-9 score for those on antidepressants was 5.8 (5.2), with no statistically significant difference between medication groups (F[2, 409] = 1.48, p = 0.23); just seven (4.9%) of those receiving anxiolytics met criteria for an anxiety disorder, which was not significantly different than other medication classes (χ (2) = 0.83, p = 0.66). Overall, 197 (47.8%) of the sample did not meet criteria for a mental health disorder. Just 69 (28.8%) of those on antidepressants reported depression as the self-reported reason for taking the medication, while 91 (22.8%) of the total reported poor sleep or stressful life events as the reason.
In this sample, many older persons received psychotropic medications despite low symptomatology, increasing the costs of care and possible exposure to unnecessary side effects. It is important to understand perceived benefit to both patient and provider of such prescribing patterns and work towards minimizing unnecessary use.
本研究旨在探讨非精神科医生为新开始使用抗抑郁药、抗焦虑药或抗精神病药的非住院老年患者的行为健康症状和特征。
宾夕法尼亚州医药援助合同(PACE)中参与的老年患者自然队列研究。
地点/参与者:宾夕法尼亚州的非住院成年人。
包括Blessed 定向-记忆-集中测试(BOMC)、迷你国际神经精神访谈(包括精神病、躁狂症、广泛性焦虑症[GAD]、惊恐障碍和酒精滥用/依赖模块)、患者健康问卷-9(PHQ-9)、佩尔克自杀意念量表和医疗结果调查(SF-12)在内的标准化量表。
参与者主要为女性(83.7%),平均年龄为 79.2 岁(标准差为 7.1)。服用抗抑郁药者的平均 PHQ-9 得分为 5.8(5.2),药物组之间无统计学差异(F[2,409] = 1.48,p = 0.23);服用抗焦虑药者中仅有 7 人(4.9%)符合焦虑障碍标准,与其他药物类别无显著差异(χ(2)= 0.83,p = 0.66)。总体而言,样本中有 197 人(47.8%)不符合精神健康障碍标准。仅有 69 名(28.8%)服用抗抑郁药者报告抑郁是他们服药的自我报告原因,而总样本中有 91 名(22.8%)报告睡眠不佳或生活压力事件是原因。
在本样本中,许多老年人接受了精神药物治疗,尽管症状较轻,但增加了医疗费用,并可能使他们面临不必要的副作用。了解患者和提供者对这种处方模式的感知益处非常重要,并努力尽量减少不必要的使用。