Department of Chemical Biology, College of Chemistry and Chemical Engineering, and the Key Laboratory for Chemical Biology of Fujian Province, Xiamen University, Xiamen, China 361005.
Org Biomol Chem. 2011 Oct 26;9(22):7652-4. doi: 10.1039/c1ob06448g. Epub 2011 Sep 23.
A chromogenic and fluorogenic detection of aldehydes was achieved via analyte triggered opening of the deoxylactam of N-(rhodamine B)-deoxylactam-ethylenediamine (dRB-EDA). The utility of the sensor was demonstrated by fluorescent labeling of aldehyde-displaying sialoproteins on cell surfaces.
通过分析物触发 N-(若丹明 B)-去氧乳酰胺-乙二胺(dRB-EDA)的去氧乳酰胺的开环反应，实现了对醛类的显色和荧光检测。该传感器通过对细胞表面展示醛基的唾液酸蛋白进行荧光标记，展示了其在实际中的应用。
