抗菌药物发现中使用的基本微生物学技术。 - Suppr

Suppr

超能文献

Basic microbiological techniques used in antibacterial drug discovery.

作者信息

Motyl Mary, Dorso Karen, Barrett John, Giacobbe Robert

机构信息

Merck and Co., Inc., Rahway, New Jersey, USA.

出版信息

Curr Protoc Pharmacol. 2006 Jan;Chapter 13:Unit13A.3. doi: 10.1002/0471141755.ph13a03s31.

DOI:10.1002/0471141755.ph13a03s31

PMID:21953398

Abstract

摘要

相似文献

Basic microbiological techniques used in antibacterial drug discovery.抗菌药物发现中使用的基本微生物学技术。

Curr Protoc Pharmacol. 2006 Jan;Chapter 13:Unit13A.3. doi: 10.1002/0471141755.ph13a03s31.

Confronting the challenges of discovery of novel antibacterial agents.应对新型抗菌剂发现的挑战。

Bioorg Med Chem Lett. 2014 Aug 15;24(16):3683-9. doi: 10.1016/j.bmcl.2014.06.053. Epub 2014 Jun 26.

Blood cultures.血培养

Br J Hosp Med. 1985 May;33(5):272-4.

[Value of the antibiogram technic for the treatment of urogenital infection with Ureaplasma (author's transl)].[尿素支原体所致泌尿生殖系统感染治疗中抗菌谱技术的价值（作者译）]

Sem Hop. 1979;55(13-14):670-7.

[The rapid microbiological control of the efficacy of the antibacterial therapy of bacteremia and septicemia].[菌血症和败血症抗菌治疗疗效的快速微生物学控制]

Urol Nefrol (Mosk). 1997 May-Jun(3):8-13.

Sensitivity of Vibrio parahaemolyticus to antibacterial agents.副溶血性弧菌对抗菌剂的敏感性。

Indian J Med Res. 1973 Mar;61(3):324-9.

Unconventional screening approaches for antibiotic discovery.非传统的抗生素发现筛选方法。

Ann N Y Acad Sci. 2015 Sep;1354:54-66. doi: 10.1111/nyas.12803. Epub 2015 Jun 22.

Application of SBDD to the discovery of new antibacterial drugs.基于结构的药物设计（SBDD）在新型抗菌药物发现中的应用。

Methods Mol Biol. 2012;841:291-319. doi: 10.1007/978-1-61779-520-6_13.

[Sensitivity of the main causative agents of gas gangrene to currently available antibacterial drugs].[气性坏疽主要致病菌对现有抗菌药物的敏感性]

Antibiot Khimioter. 1990 Apr;35(4):49-51.

Alternative natural sources for a new generation of antibacterial agents.新一代抗菌剂的替代天然来源。

Int J Antimicrob Agents. 2013 Sep;42(3):195-201. doi: 10.1016/j.ijantimicag.2013.05.004. Epub 2013 Jun 21.

引用本文的文献

Improvement of the Antimicrobial Peptide Activity by Means of Chitosan-Based Nanoparticles.通过基于壳聚糖的纳米颗粒提高抗菌肽活性。

Biotechnol J. 2025 Jun;20(6):e70062. doi: 10.1002/biot.70062.

Synergistic potential of Leu-teixobactin and cefepime against multidrug-resistant Staphylococcus aureus.Leu-teixobactin 与头孢吡肟联合应用对多重耐药金黄色葡萄球菌的协同作用。

BMC Microbiol. 2024 Oct 29;24(1):442. doi: 10.1186/s12866-024-03577-x.

Fighting fibrin with fibrin: Vancomycin delivery into coagulase-mediated Staphylococcus aureus biofilms via fibrin-based nanoparticle binding.以纤维蛋白对抗纤维蛋白：通过基于纤维蛋白的纳米颗粒结合将万古霉素递送至凝固酶介导的金黄色葡萄球菌生物膜中。

J Biomed Mater Res A. 2024 Dec;112(12):2071-2085. doi: 10.1002/jbm.a.37760. Epub 2024 Jun 14.

Increased Absorption and Inhibitory Activity against spp. of Imidazole Derivatives in Synergistic Association with a Surface Active Agent.与表面活性剂协同作用时咪唑衍生物对 spp. 的吸收增加及抑制活性增强。

Microorganisms. 2023 Dec 27;12(1):51. doi: 10.3390/microorganisms12010051.

Identification and Analysis of Antimicrobial Activities from a Model Moss .从一种模式苔藓中鉴定和分析抗菌活性

Metabolites. 2023 Feb 27;13(3):350. doi: 10.3390/metabo13030350.

Activity of Binary Combinations of Natural Phenolics and Synthetic Food Preservatives against Food Spoilage Yeasts.天然酚类化合物与合成食品防腐剂二元组合对食品腐败酵母的活性

Foods. 2023 Mar 22;12(6):1338. doi: 10.3390/foods12061338.

An Efficient Disinfectant, Composite Material {SLS@[Zn(CitH)]} as Ingredient for Development of Sterilized and Non Infectious Contact Lens.一种高效消毒剂，复合材料{SLS@[Zn(CitH)]}作为开发无菌和无感染性隐形眼镜的成分。

Antibiotics (Basel). 2019 Nov 7;8(4):213. doi: 10.3390/antibiotics8040213.

Pharmacodynamics of ClpP-Activating Antibiotic Combinations against Gram-Positive Pathogens.ClpP 激活型抗生素组合对革兰氏阳性病原体的药效学研究。

Antimicrob Agents Chemother. 2019 Dec 20;64(1). doi: 10.1128/AAC.01554-19.

Essential Oil, Extracts, and Sesquiterpenes Obtained From the Heartwood of Act as Potential Inhibitors of the NorA Multidrug Efflux Pump.从[植物名称]心材中获得的精油、提取物和倍半萜作为NorA多药外排泵的潜在抑制剂。（注：原文中Act前缺少具体植物名称）

Front Microbiol. 2019 Feb 26;10:337. doi: 10.3389/fmicb.2019.00337. eCollection 2019.

and Effects of a ClpP-Activating Antibiotic against Vancomycin-Resistant Enterococci.克拉仙（ClpP）激活抗生素对万古霉素耐药肠球菌的作用。

Antimicrob Agents Chemother. 2018 Jul 27;62(8). doi: 10.1128/AAC.00424-18. Print 2018 Aug.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验