Tangutur Naveen Kumar R, Medvedev Sabeen Faruqui, Regenstein Fred, Balart Luis A
Section of Gastroenterology and Hepatology, Tulane University Health Sciences Center, New Orleans, USA.
J La State Med Soc. 2011 Jul-Aug;163(4):185-90.
The rising incidence of hepatocellular carcinoma (HCC) in the United States is of importance to all practitioners. Louisiana has one of the highest HCC related mortality rates in the United States. Our study reviews the experience with HCC at Tulane University Medical Center from 2003 to 2009 and compares our experience with the national experience. Our data shows that from 2003 to 2009, the number of new HCC cases seen at Tulane increased by 300%, paralleling reported national trends. Infection with the hepatitis C virus (HCV) leading to cirrhosis is the most common factor in the development of HCC. In addition, our data suggests that diabetes may play a role in the development of HCC. Our study confirms the rising incidence of HCC in Louisiana and provides strong support for the rapid implementation of statewide surveillance programs for the early detection of HCC in individuals at risk.
美国肝细胞癌(HCC)发病率的上升对所有从业者来说都至关重要。路易斯安那州是美国HCC相关死亡率最高的地区之一。我们的研究回顾了2003年至2009年杜兰大学医学中心治疗HCC的经验,并将我们的经验与全国情况进行比较。我们的数据显示,2003年至2009年,杜兰大学新确诊的HCC病例数增加了300%,与全国报告的趋势一致。丙型肝炎病毒(HCV)感染导致肝硬化是HCC发生的最常见因素。此外,我们的数据表明糖尿病可能在HCC的发生中起作用。我们的研究证实了路易斯安那州HCC发病率的上升,并为迅速实施全州范围的监测计划以早期发现高危个体的HCC提供了有力支持。