Department of Otolaryngology, Head and Neck Surgery, University of Tübingen, Germany.
Diagn Pathol. 2011 Sep 30;6:94. doi: 10.1186/1746-1596-6-94.
Dendritic cell tumors are extremely rare neoplasms arising from antigen-presenting cells of the immune system. We report a case of a 69-year-old man with an unremarkable medical history who presented with a 2-months history of a gradually enlarging painless, firm, mobile, 2 × 2-cm swelling at the caudal pole of the left parotid gland without systemic symptoms. Histologically, the tumor consisted of a spindle cell proliferation in an intraparotideal lymph node. Based on the histopathologic, immunohistochemical and electron microscopic findings, a dendritic cell tumor, not otherwise specified (NOS) in an intraparotideal lymph node was diagnosed.The patient underwent complete tumor resection, and is currently free of disease, 2 years after surgery. These extremely rare tumors must be distinguished from other more common tumors in the salivary glands. Awareness that dendritic cell tumors may occur in this localization, careful histologic evaluation and ancillary immunohistochemical and electron microscopical analyses should allow for recognition of this entity.
树突细胞肿瘤是一种极为罕见的肿瘤，起源于免疫系统的抗原提呈细胞。我们报告了一例 69 岁男性病例，无明显病史，表现为左腮腺尾部有一个 2 个月逐渐增大的无痛性、坚实、可移动的 2×2cm 肿块，无全身症状。组织学上，肿瘤由一个位于腮腺内淋巴结的梭形细胞增殖组成。根据组织病理学、免疫组织化学和电子显微镜检查结果，诊断为腮腺内淋巴结未特指的树突细胞肿瘤。患者接受了完全肿瘤切除术，术后 2 年无疾病复发。这些极为罕见的肿瘤必须与其他更常见的唾液腺肿瘤区分开来。认识到树突细胞肿瘤可能发生在这个部位，仔细的组织学评估以及辅助的免疫组织化学和电子显微镜分析应该能够识别出这种实体。
