Arushanian E B, Baturin V A
Farmakol Toksikol. 1990 Mar-Apr;53(2):70-5.
The conception of the specific activity of antidepressants is considered from the chronobiological positions. Depression can be based on phasic dissociation between different periods and first of all circadian fluctuation of some physiological functions. Various antidepressants modified biorhythms and promoted their resynchronization. This action probably depended on its influence on the activity of the cerebral pacemaker structures (suprachiasmatic nuclei, hypothalamus and pineal gland).
从生物钟学的角度考虑抗抑郁药的比活性概念。抑郁症可能基于不同时期之间的阶段性解离，首先是某些生理功能的昼夜节律波动。各种抗抑郁药可改变生物节律并促进其重新同步。这种作用可能取决于其对大脑起搏器结构（视交叉上核、下丘脑和松果体）活动的影响。
