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在越南农村对 823 名 5 岁以下儿童进行的 28 天随访中,发现轻度急性呼吸道感染时过度使用抗生素。

Unnecessary antibiotic use for mild acute respiratory infections during 28-day follow-up of 823 children under five in rural Vietnam.

机构信息

Division of Global Health (IHCAR), Department of Public Health Sciences, Karolinska Institutet, Nobel väg 9, SE 171 77 Stockholm, Sweden.

出版信息

Trans R Soc Trop Med Hyg. 2011 Nov;105(11):628-36. doi: 10.1016/j.trstmh.2011.07.015. Epub 2011 Sep 29.

DOI:10.1016/j.trstmh.2011.07.015
PMID:21962293
Abstract

Few prospective studies regarding antibiotic use for mild acute respiratory infections (ARI) have been conducted in community settings. This paper aimed to assess knowledge of children's caregivers and actual antibiotic use for children under five and to identify factors associated with antibiotic treatment for mild ARIs. Caregivers in 828 households in Bavi, Vietnam, were interviewed using a structured questionnaire assessing both knowledge and practice. Subsequently, 823 children were followed for 28 days to collect information regarding symptoms and drug use. For management of ARIs, only 13% of caregivers demonstrated correct overall knowledge in accordance with standard guidelines. The symptoms of the most recent illness were consistent with mild ARI in 79% of cases, and antibiotics were used in 71% of these. During the 28-day period, 62% of children had been given antibiotics and 63% of antibiotic courses were used for mild ARIs. One-half of the mild ARI episodes and 63% of the children with mild ARIs were treated with antibiotics. Most of the unnecessary antibiotic treatment was recommended by healthcare providers (82%). Most of the children had been administered antibiotics for common colds, although most caregivers believed that antibiotics were not required. Antibiotics were unnecessarily recommended at health facilities in the area.

摘要

针对轻度急性呼吸道感染(ARI)在社区环境中使用抗生素的前瞻性研究较少。本文旨在评估儿童护理者对儿童(五岁以下)使用抗生素的知识和实际情况,并确定与轻度ARI 抗生素治疗相关的因素。在越南巴维的 828 户家庭中,使用结构化问卷对护理者进行了访谈,以评估知识和实践。随后,对 823 名儿童进行了 28 天的随访,以收集有关症状和药物使用的信息。对于 ARI 的管理,只有 13%的护理者按照标准指南显示出正确的总体知识。最近一次疾病的症状符合轻度ARI 的比例为 79%,其中 71%使用了抗生素。在 28 天期间,62%的儿童使用了抗生素,63%的抗生素疗程用于轻度ARI。一半的轻度ARI 发作和 63%的轻度ARI 儿童接受了抗生素治疗。大多数不必要的抗生素治疗是由医疗保健提供者推荐的(82%)。大多数儿童因普通感冒而服用抗生素,尽管大多数护理者认为不需要抗生素。该地区的卫生机构不必要地推荐了抗生素。

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