Friends Research Institute, Inc., 1040 Park Avenue, Baltimore, MD 21201, USA.
Drug Alcohol Depend. 2012 Apr 1;122(1-2):55-60. doi: 10.1016/j.drugalcdep.2011.09.009. Epub 2011 Sep 29.
To expand its public-sector treatment capacity, Baltimore City made buprenorphine treatment accessible to low-income, largely African American residents. This study compares the characteristics of patients entering methadone treatment vs. buprenorphine treatment to determine whether BT was attracting different types of patients.
Participants consisted of two samples of adult heroin-dependent African Americans. The first sample was newly admitted to a health center or a mental health center providing buprenorphine (N=200), and the second sample was newly admitted to one of two hospital-based methadone programs (N=178). The Addiction Severity Index (ASI) and the Friends Supplemental Questionnaire were administered at treatment entry and data were analyzed with logistic regression.
BT participants were more likely to be female (p=.017) and less likely to inject (p=.001). Participants with only prior buprenorphine treatment experience were nearly five time more likely to enter buprenorphine than methadone treatment (p<.001). Those with experience with both treatments were more than twice as likely to enter BT (OR=2.7, 95% CI=1.11-6.62; p=.028). In the 30 days prior to treatment entry, BT participants reported more days of medical problems (p=.002) and depression (p=.044), and were more likely to endorse a lifetime history of depression (p<.001).
Methadone and buprenorphine treatment provided in the public sector may attract different patient subpopulations. Providing buprenorphine treatment through drug treatment programs co-located with a health and mental health center may have accounted for their higher rates of medical and psychiatric problems and appears to be useful in attracting a diverse group of patients into public-sector funded treatment.
为了扩大公共部门的治疗能力,巴尔的摩市让低收入、以非裔美国人为主的居民能够获得丁丙诺啡治疗。本研究比较了进入美沙酮治疗和丁丙诺啡治疗的患者特征,以确定 BT 是否吸引了不同类型的患者。
参与者由两组成年非裔美国海洛因依赖者组成。第一组是新进入健康中心或提供丁丙诺啡的心理健康中心的患者(N=200),第二组是新进入两家医院美沙酮项目的患者(N=178)。在治疗开始时,对参与者进行成瘾严重程度指数(ASI)和朋友补充问卷的评估,并使用逻辑回归分析数据。
BT 组的参与者更有可能是女性(p=.017),不太可能注射(p=.001)。只有丁丙诺啡治疗经验的参与者进入丁丙诺啡治疗的可能性是美沙酮治疗的近五倍(p<.001)。有两种治疗经验的参与者进入 BT 的可能性是美沙酮治疗的两倍多(OR=2.7,95% CI=1.11-6.62;p=.028)。在治疗开始前的 30 天内,BT 组报告的医疗问题(p=.002)和抑郁(p=.044)天数更多,并且更有可能有过抑郁的终生病史(p<.001)。
公共部门提供的美沙酮和丁丙诺啡治疗可能吸引不同的患者亚群。在与健康和心理健康中心同地设立的药物治疗项目中提供丁丙诺啡治疗,可能导致他们出现更高的医疗和精神健康问题,并且似乎有助于吸引更多不同背景的患者进入公共部门资助的治疗。