Friends Research Institute, 1040 Park Avenue, Baltimore, MD 21201, USA.
Am J Addict. 2013 May-Jun;22(3):285-91. doi: 10.1111/j.1521-0391.2012.12004.x.
Recent policy initiatives in Baltimore City, MD significantly reduced access disparities between methadone and buprenorphine in the publicly funded treatment sector.
This study examines reasons for choosing buprenorphine over methadone among patients with access to both medications.
This study was embedded within a larger clinical trial conducted at two outpatient substance abuse treatment programs offering buprenorphine. Qualitative and quantitative data on treatment choice were collected for new patients starting buprenorphine treatment (n = 80). The sample consisted of predominantly urban African American (94%) heroin users who had prior experience with non-prescribed street buprenorphine (85%), and opioid agonist treatment (68%). Qualitative data were transcribed and coded for themes, while quantitative data were analyzed using descriptive and bivariate statistics.
Participants typically conveyed their choice of buprenorphine treatment as a decision against methadone. Buprenorphine was perceived as a helpful medication while methadone was perceived as a harmful narcotic with multiple unwanted physical effects. Positive experiences with non-prescribed "street buprenorphine" were a central factor in participants' decisions to seek buprenorphine treatment.
Differences in service structure between methadone and buprenorphine did not strongly influence treatment-seeking decisions in this sample. Personal experiences with medications and the street narrative surrounding them play an important role in treatment selection decisions.
This study characterizes important decision factors that underlie patients' selection of buprenorphine over methadone treatment.
马里兰州巴尔的摩市最近的政策举措大大减少了公费治疗领域中美沙酮和丁丙诺啡之间的获取差距。
本研究旨在探讨在可同时获得这两种药物的患者中选择丁丙诺啡而非美沙酮的原因。
这项研究是嵌入在两个提供丁丙诺啡的门诊药物滥用治疗项目中进行的更大规模临床试验的一部分。对开始丁丙诺啡治疗的新患者(n=80)收集了关于治疗选择的定性和定量数据。该样本主要由有非处方街头丁丙诺啡(85%)和阿片类激动剂治疗(68%)既往经验的城市非洲裔美国(94%)海洛因使用者组成。定性数据被转录并编码为主题,而定量数据则使用描述性和双变量统计进行分析。
参与者通常表示他们选择丁丙诺啡治疗是反对美沙酮的决定。丁丙诺啡被认为是一种有益的药物,而美沙酮则被认为是一种有害的麻醉剂,具有多种不良的身体影响。非处方“街头丁丙诺啡”的积极体验是参与者寻求丁丙诺啡治疗的决定的一个核心因素。
在这个样本中,美沙酮和丁丙诺啡的服务结构差异并没有强烈影响治疗寻求决策。药物的个人经验及其周围的街头叙事在治疗选择决策中起着重要作用。
本研究描述了患者选择丁丙诺啡而非美沙酮治疗的重要决策因素。