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本文引用的文献

1
African American patients seeking treatment in the public sector: characteristics of buprenorphine vs. methadone patients.非裔美国患者在公共部门寻求治疗:丁丙诺啡与美沙酮患者的特征比较。
Drug Alcohol Depend. 2012 Apr 1;122(1-2):55-60. doi: 10.1016/j.drugalcdep.2011.09.009. Epub 2011 Sep 29.
2
Diversion and abuse of buprenorphine: findings from national surveys of treatment patients and physicians.丁丙诺啡的转移和滥用:来自治疗患者和医生全国调查的结果。
Drug Alcohol Depend. 2012 Jan 1;120(1-3):190-5. doi: 10.1016/j.drugalcdep.2011.07.019. Epub 2011 Aug 21.
3
Redefining retention: recovery from the patient's perspective.重新定义保留:从患者角度看恢复。
J Psychoactive Drugs. 2011 Apr-Jun;43(2):99-107. doi: 10.1080/02791072.2011.587392.
4
Patterns in admission delays to outpatient methadone treatment in the United States.美国门诊美沙酮治疗入院延迟的模式。
J Subst Abuse Treat. 2011 Dec;41(4):431-9. doi: 10.1016/j.jsat.2011.06.005. Epub 2011 Aug 6.
5
Patients' Reasons for Choosing Office-based Buprenorphine: Preference for Patient-Centered Care.患者选择门诊丁丙诺啡的原因:以患者为中心的护理偏好。
J Addict Med. 2010 Dec;4(4):204-10. doi: 10.1097/ADM.0b013e3181cc9610.
6
Antecedents and correlates of methadone treatment entry: a comparison of out-of-treatment and in-treatment cohorts.美沙酮治疗进入的前因和相关因素:治疗前和治疗中队列的比较。
Drug Alcohol Depend. 2011 May 1;115(1-2):23-9. doi: 10.1016/j.drugalcdep.2010.10.016. Epub 2010 Dec 3.
7
The SUMMIT trial: a field comparison of buprenorphine versus methadone maintenance treatment.SUMMIT 试验:丁丙诺啡与美沙酮维持治疗的现场比较。
J Subst Abuse Treat. 2010 Dec;39(4):340-52. doi: 10.1016/j.jsat.2010.07.009.
8
Self-treatment: illicit buprenorphine use by opioid-dependent treatment seekers.自我治疗:阿片类药物依赖治疗寻求者的非法丁丙诺啡使用。
J Subst Abuse Treat. 2010 Jul;39(1):41-50. doi: 10.1016/j.jsat.2010.03.014.
9
Diversion of buprenorphine/naloxone coformulated tablets in a region with high prescribing prevalence.丁丙诺啡/纳洛酮复方片剂在高处方流行地区的转移。
J Addict Dis. 2009 Jul;28(3):226-31. doi: 10.1080/10550880903014767.
10
Premature discharge from methadone treatment: patient perspectives.美沙酮治疗提前出院:患者观点。
J Psychoactive Drugs. 2009 Sep;41(3):285-96. doi: 10.1080/02791072.2009.10400539.

患者在城市平等准入系统中选择丁丙诺啡而非美沙酮的观点。

Patient perspectives on choosing buprenorphine over methadone in an urban, equal-access system.

机构信息

Friends Research Institute, 1040 Park Avenue, Baltimore, MD 21201, USA.

出版信息

Am J Addict. 2013 May-Jun;22(3):285-91. doi: 10.1111/j.1521-0391.2012.12004.x.

DOI:10.1111/j.1521-0391.2012.12004.x
PMID:23617873
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4215541/
Abstract

BACKGROUND

Recent policy initiatives in Baltimore City, MD significantly reduced access disparities between methadone and buprenorphine in the publicly funded treatment sector.

OBJECTIVES

This study examines reasons for choosing buprenorphine over methadone among patients with access to both medications.

METHOD

This study was embedded within a larger clinical trial conducted at two outpatient substance abuse treatment programs offering buprenorphine. Qualitative and quantitative data on treatment choice were collected for new patients starting buprenorphine treatment (n = 80). The sample consisted of predominantly urban African American (94%) heroin users who had prior experience with non-prescribed street buprenorphine (85%), and opioid agonist treatment (68%). Qualitative data were transcribed and coded for themes, while quantitative data were analyzed using descriptive and bivariate statistics.

RESULTS

Participants typically conveyed their choice of buprenorphine treatment as a decision against methadone. Buprenorphine was perceived as a helpful medication while methadone was perceived as a harmful narcotic with multiple unwanted physical effects. Positive experiences with non-prescribed "street buprenorphine" were a central factor in participants' decisions to seek buprenorphine treatment.

CONCLUSIONS

Differences in service structure between methadone and buprenorphine did not strongly influence treatment-seeking decisions in this sample. Personal experiences with medications and the street narrative surrounding them play an important role in treatment selection decisions.

SCIENTIFIC SIGNIFICANCE

This study characterizes important decision factors that underlie patients' selection of buprenorphine over methadone treatment.

摘要

背景

马里兰州巴尔的摩市最近的政策举措大大减少了公费治疗领域中美沙酮和丁丙诺啡之间的获取差距。

目的

本研究旨在探讨在可同时获得这两种药物的患者中选择丁丙诺啡而非美沙酮的原因。

方法

这项研究是嵌入在两个提供丁丙诺啡的门诊药物滥用治疗项目中进行的更大规模临床试验的一部分。对开始丁丙诺啡治疗的新患者(n=80)收集了关于治疗选择的定性和定量数据。该样本主要由有非处方街头丁丙诺啡(85%)和阿片类激动剂治疗(68%)既往经验的城市非洲裔美国(94%)海洛因使用者组成。定性数据被转录并编码为主题,而定量数据则使用描述性和双变量统计进行分析。

结果

参与者通常表示他们选择丁丙诺啡治疗是反对美沙酮的决定。丁丙诺啡被认为是一种有益的药物,而美沙酮则被认为是一种有害的麻醉剂,具有多种不良的身体影响。非处方“街头丁丙诺啡”的积极体验是参与者寻求丁丙诺啡治疗的决定的一个核心因素。

结论

在这个样本中,美沙酮和丁丙诺啡的服务结构差异并没有强烈影响治疗寻求决策。药物的个人经验及其周围的街头叙事在治疗选择决策中起着重要作用。

科学意义

本研究描述了患者选择丁丙诺啡而非美沙酮治疗的重要决策因素。