Department of Biochemistry and Molecular Biology, University of Massachusetts, Lederle Graduate Research Tower, Amherst, MA 01003, United States.
Curr Opin Plant Biol. 2011 Dec;14(6):632-41. doi: 10.1016/j.pbi.2011.09.001. Epub 2011 Sep 29.
The plant cell wall provides form and integrity to the cell as well as a dynamic interface between a cell and its environment. Therefore mechanisms capable of policing changes in the cell wall, signaling cellular responses including those that would feedback regulate cell wall properties are expected to play important roles in facilitating growth and ensuring survival. Discoveries in the last few years that the Arabidopsis THESEUS 1 receptor-like kinase (RLK) may function as a sensor for cell wall defects to regulate growth and that its relatives FERONIA and ANXURs regulate pollen tube integrity imply strongly that they play key roles in cell wall-related processes. Furthermore, FERONIA acts as a cell surface regulator for RAC/ROP GTPases and activates production of reactive oxygen species which are, respectively, important molecular switches and mediators for diverse processes. These findings position the THESEUS 1/FERONIA family RLKs as surface regulators and potential cell wall sensors capable of broadly and profoundly impacting cellular pathways in response to diverse signals.
植物细胞壁为细胞提供形态和完整性，并作为细胞与其环境之间的动态界面。因此，能够监管细胞壁变化、发出包括反馈调节细胞壁特性的细胞反应信号的机制，有望在促进生长和确保生存方面发挥重要作用。在过去几年中发现，拟南芥 THESEUS 1 受体样激酶（RLK）可能作为细胞壁缺陷的传感器，以调节生长，其同源物 FERONIA 和 ANXURs 调节花粉管完整性，这强烈暗示它们在细胞壁相关过程中发挥关键作用。此外，FERONIA 作为 RAC/ROP GTPases 的细胞表面调节剂，激活活性氧的产生，而活性氧分别是多种过程的重要分子开关和介质。这些发现将 THESEUS 1/FERONIA 家族 RLK 定位为表面调节剂和潜在的细胞壁传感器，能够广泛而深刻地响应各种信号，影响细胞途径。
