University of California, Los Angeles, 619 Charles E. Young Dr. East, La Kretz Hall, Suite 300, Box 951496, Los Angeles, CA 90095-1496, USA.
Vet Microbiol. 2012 Apr 23;156(1-2):189-92. doi: 10.1016/j.vetmic.2011.09.003. Epub 2011 Sep 12.
Although swine origin A/H1N1/2009 influenza virus (hereafter "pH1N1″) has been detected in swine in 20 countries, there has been no published surveillance of the virus in African livestock. The objective of this study was to assess the circulation of influenza A viruses, including pH1N1 in swine in Cameroon, Central Africa. We collected 108 nasal swabs and 98 sera samples from domestic pigs randomly sampled at 11 herds in villages and farms in Cameroon. pH1N1 was isolated from two swine sampled in northern Cameroon in January 2010. Sera from 28% of these herds were positive for influenza A by competitive ELISA and 92.6% of these swine showed cross reactivity with pandemic A/H1N1/2009 influenza virus isolated from humans. These results provide the first evidence of this virus in the animal population in Africa. In light of the significant role of swine in the ecology of influenza viruses, our results call for greater monitoring and study in Central Africa.
虽然在 20 个国家的猪群中检测到了甲型 H1N1/2009 流感病毒（以下简称“pH1N1”），但目前还没有对非洲牲畜中该病毒的监测情况进行公布。本研究的目的是评估包括 pH1N1 在内的甲型流感病毒在喀麦隆猪群中的流行情况。我们从喀麦隆村庄和农场的 11 个畜群中随机采集了 108 份鼻拭子和 98 份血清样本。2010 年 1 月，我们从喀麦隆北部的两头猪身上分离到了 pH1N1。通过竞争性 ELISA 检测，这些畜群中有 28%的血清呈甲型流感阳性，其中 92.6%的猪与从人类中分离到的大流行性 A/H1N1/2009 流感病毒发生交叉反应。这些结果为该病毒在非洲动物种群中的存在提供了首个证据。鉴于猪在流感病毒生态学中的重要作用，我们的研究结果呼吁在中非地区加强监测和研究。
