Yamashita Mitsuaki, Ueda Kazunori, Sakaguchi Koichi, Tokuda Harukuni, Iida Akira
Faculty of Pharmacy, Takasaki University of Health and Welfare, Takasaki, Japan.
Chem Pharm Bull (Tokyo). 2011;59(10):1289-93. doi: 10.1248/cpb.59.1289.
In this paper, a concise one-pot method for the construction of benzo[f]indole-4,9-dione motifs is described. These transformations proceed via a sequential palladium- and copper-catalyzed coupling reaction of 1,4-naphthoquinones with terminal acetylenes, followed by a copper-catalyzed intramolecular cyclization reaction of the resulting coupling product.
本文描述了一种简洁的一锅法构建苯并[f]吲哚-4,9-二酮基序的方法。这些转化过程是通过1,4-萘醌与末端乙炔的钯和铜催化的顺序偶联反应进行的，随后是所得偶联产物的铜催化分子内环化反应。
