由1,4-萘醌和末端炔烃一锅法合成苯并[f]吲哚-4,9-二酮
One-pot synthesis of benzo[f]indole-4,9-diones from 1,4-naphthoquinones and terminal acetylenes.
作者信息
Yamashita Mitsuaki, Ueda Kazunori, Sakaguchi Koichi, Tokuda Harukuni, Iida Akira
机构信息
Faculty of Pharmacy, Takasaki University of Health and Welfare, Takasaki, Japan.
出版信息
Chem Pharm Bull (Tokyo). 2011;59(10):1289-93. doi: 10.1248/cpb.59.1289.
PMID:21963641
Abstract
In this paper, a concise one-pot method for the construction of benzo[f]indole-4,9-dione motifs is described. These transformations proceed via a sequential palladium- and copper-catalyzed coupling reaction of 1,4-naphthoquinones with terminal acetylenes, followed by a copper-catalyzed intramolecular cyclization reaction of the resulting coupling product.
摘要
本文描述了一种简洁的一锅法构建苯并[f]吲哚-4,9-二酮基序的方法。这些转化过程是通过1,4-萘醌与末端乙炔的钯和铜催化的顺序偶联反应进行的，随后是所得偶联产物的铜催化分子内环化反应。
Zotero 插件