Department of Psychology, University of Colorado at ColoradoSprings, 1420 Austin Bluffs Parkway, Colorado Springs, CO 80918, USA.
Clin Psychol Rev. 2011 Dec;31(8):1239-46. doi: 10.1016/j.cpr.2011.08.001. Epub 2011 Aug 24.
Depression and diabetes are both serious chronic conditions common in Western cultures. These conditions impart a significant burden on the patients and society. Depression is often comorbid with chronic illness, and past research has found an increased prevalence of depressive symptoms in patients with Type 2 Diabetes Mellitus (T2DM). However, the exact nature and direction of this relationship are unknown. Depression is often thought to be a consequence of diabetes, perhaps due to the burden of chronic illness. Research has also suggested that depression may be a risk factor for development of diabetes, in part due to biochemical changes in depression and in part because of a reduction of health care behaviors in individuals with depression. This paper reviews the literature behind both lines of investigation and includes special diagnostic and clinical considerations for at risk populations. We discuss clinical implications, limitations of current research, and areas of interest for future research.
抑郁和糖尿病都是在西方文化中常见的严重慢性疾病。这些疾病给患者和社会带来了巨大的负担。抑郁常常与慢性疾病共病，过去的研究发现，2 型糖尿病（T2DM）患者中抑郁症状的患病率增加。然而，这种关系的确切性质和方向尚不清楚。抑郁通常被认为是糖尿病的后果，可能是由于慢性疾病的负担。研究还表明，抑郁可能是糖尿病发病的一个危险因素，部分原因是抑郁的生化变化，部分原因是抑郁患者的医疗保健行为减少。本文综述了这两个研究方向的文献，并包括了高危人群的特殊诊断和临床注意事项。我们讨论了临床意义、当前研究的局限性以及未来研究的兴趣领域。
