Kim Young-Chan, Han Kyungdo, Kim Suhyung, Um Yoo Hyun, Kim Tae-Won, Seo Ho Jun, Hong Seung-Chul, Jeong Jong-Hyun
Department of Psychiatry, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Department of Statistics and Actuarial Science, Soongsil University, Seoul, Korea.
Clin Psychopharmacol Neurosci. 2025 Aug 31;23(3):476-487. doi: 10.9758/cpn.25.1310.
To investigate relationships between diabetes, diabetes duration, and psychiatric difficulties using data from a nationwide survey and to examine associations between psychiatric difficulties and physician diagnosis, treatment status, and glycemic control in diabetes patients by performing subgroup analyses.
Data from the 2022 Korea National Health and Nutrition Examination Survey were analyzed. A representative sample of 4,475 adults aged 19 years or older was obtained using stratified, multistage, clustered sampling. Psychiatric difficulties were assessed using PHQ-9 for depression, GAD-7 for anxiety, and face-to-face interviews for suicidality. Diabetes patients were categorized by diabetes duration (< 5, 5-9, 10-14, and ≥ 15 years). Statistical models were adjusted for demographic and clinical covariates.
Diabetes patients were significantly more likely to experience depression than controls (aOR = 1.818). Those with a diabetes duration of ≥ 15 years showed significant associations with depression (aOR = 2.830), suicidal ideation (aOR = 2.496), and suicidal plans (aOR = 4.604). Such associations were not found in shorter duration groups. Subgroup analyses revealed links between suicidal ideation and being diagnosed by a physician or receiving treatment. No significant associations were found between glycemic control and psychiatric difficulties.
Depression was more prevalent in diabetes patients than in controls. A diabetes duration of ≥ 15 years was significantly linked to higher rates of depression and suicidality. Routine psychiatric screenings after 15 years of diabetes duration could enhance public health strategies. Addressing societal stigma and alleviating burdens of diabetes management might improve mental health outcomes.
利用一项全国性调查的数据，研究糖尿病、糖尿病病程与精神障碍之间的关系，并通过进行亚组分析，检验糖尿病患者精神障碍与医生诊断、治疗状况及血糖控制之间的关联。
对2022年韩国国民健康与营养检查调查的数据进行分析。采用分层、多阶段、整群抽样方法，选取了4475名19岁及以上成年人的代表性样本。使用PHQ-9评估抑郁、GAD-7评估焦虑，并通过面对面访谈评估自杀倾向。糖尿病患者按糖尿病病程分类（<5年、5-9年、10-14年和≥15年）。统计模型对人口统计学和临床协变量进行了调整。
糖尿病患者患抑郁症的可能性显著高于对照组（调整后比值比[aOR]=1.818）。糖尿病病程≥15年的患者与抑郁症（aOR=2.830）、自杀意念（aOR=2.496）和自杀计划（aOR=4.604）显著相关。在病程较短的组中未发现此类关联。亚组分析揭示了自杀意念与医生诊断或接受治疗之间的联系。血糖控制与精神障碍之间未发现显著关联。
糖尿病患者中抑郁症比对照组更普遍。糖尿病病程≥15年与更高的抑郁症和自杀率显著相关。糖尿病病程15年后进行常规精神筛查可加强公共卫生策略。消除社会污名并减轻糖尿病管理负担可能改善心理健康结果。
