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分散重复基因之间的减数分裂重组与异源双链体形成有关。

Meiotic recombination between dispersed repeated genes is associated with heteroduplex formation.

作者信息

Nag D K, Petes T D

机构信息

Department of Biology, University of North Carolina, Chapel Hill 27599-3280.

出版信息

Mol Cell Biol. 1990 Aug;10(8):4420-3. doi: 10.1128/mcb.10.8.4420-4423.1990.

Abstract

In Saccharomyces cerevisiae, recombination events occurring between allelic genes located on homologous chromosomes are often associated with heteroduplex formation. We found that recombination events between repeated genes on nonhomologous chromosomes (ectopic events) are also associated with the formation of heteroduplexes, indicating that classical and ectopic recombination events involve similar mechanisms.

摘要

在酿酒酵母中,发生在同源染色体上等位基因之间的重组事件通常与异源双链体的形成相关。我们发现,非同源染色体上重复基因之间的重组事件(异位事件)也与异源双链体的形成相关,这表明经典重组事件和异位重组事件涉及相似的机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d54/361006/4ae6ca28cd71/molcellb00044-0576-a.jpg

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