Jinks-Robertson S, Petes T D
Proc Natl Acad Sci U S A. 1985 May;82(10):3350-4. doi: 10.1073/pnas.82.10.3350.
We have used a genetic system that allows detection of meiotic recombination events between repeated sequences on nonhomologous chromosomes in the yeast Saccharomyces cerevisiae. We have found that recombination between these sequences occurs at a frequency of about 0.5%, and the events observed were nonreciprocal (gene conversions). Surprisingly, the frequency of conversion between the repeated genes on nonhomologous chromosomes observed in this study is similar to that observed between allelic genes. This result is discussed in connection with the role of the synaptonemal complex in meiotic recombination and with the relationship between reciprocal and nonreciprocal recombination.
我们使用了一种遗传系统，该系统能够检测酿酒酵母中非同源染色体上重复序列之间的减数分裂重组事件。我们发现这些序列之间的重组发生频率约为0.5%，并且观察到的事件是非互惠的（基因转换）。令人惊讶的是，本研究中观察到的非同源染色体上重复基因之间的转换频率与等位基因之间观察到的频率相似。结合联会复合体在减数分裂重组中的作用以及互惠和非互惠重组之间的关系对这一结果进行了讨论。
