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实体器官移植领域的新进展和热点:2011 年美国移植大会综述。

What's New, What's Hot in Solid Organ Transplantation? Summary of the American Transplant Congress 2011.

机构信息

Department of Surgery, Vanderbilt University School of Medicine, Nashville, TN, USA.

出版信息

Am J Transplant. 2011 Nov;11(11):2308-16. doi: 10.1111/j.1600-6143.2011.03774.x. Epub 2011 Oct 3.

Abstract

Breakthroughs in basic and clinical science in solid organ transplantation were presented at the American Transplant Congress 2011. Key areas of presentation included the pathogenesis of late allograft failure, immune regulation and tolerance, pathways in allograft injury, electing appropriate patients for transplantation, determining the best allocation schemes to maximize effective utilization, organ preservation, monitoring the alloimmune response and immunosuppressive management. In this review, we present highlights of the meeting. These presentations demonstrate the exciting promise in translating from the bench to affect patient care.

摘要

在 2011 年美国移植大会上展示了实体器官移植在基础和临床科学方面的突破。主要介绍的领域包括:同种异体移植物晚期失功的发病机制、免疫调节与耐受、同种异体损伤途径、选择合适的移植患者、制定最佳分配方案以最大化有效利用、器官保存、同种免疫反应监测和免疫抑制管理。在这篇综述中,我们呈现了会议的重点。这些介绍展示了从实验室到影响患者护理的令人兴奋的承诺。

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