噬菌体PRD1（一种具有包膜的细菌病毒）的衣壳蛋白

Capsomer proteins of bacteriophage PRD1, a bacterial virus with a membrane.

作者信息

Bamford J K, Bamford D H

机构信息

Department of Genetics, University of Helsinki, Finland.

出版信息

Virology. 1990 Aug;177(2):445-51. doi: 10.1016/0042-6822(90)90508-o.

DOI:10.1016/0042-6822(90)90508-o

PMID:2196741

Abstract

Bacteriophage PRD1 infecting Escherichia coli and Salmonella typhimurium translocates its membrane from the host plasma membrane to the virus particle. One obligatory component in this process is the major capsid protein. In this investigation we describe characteristics of the homomultimeric major and minor capsid proteins including the sequences of the corresponding genes. The minor capsid protein was found to contain a short collagen-like region (Gly-X-Y)6. This is the first time this motif has been reported for a prokaryotic protein.

摘要

感染大肠杆菌和鼠伤寒沙门氏菌的噬菌体PRD1将其膜从宿主质膜转移至病毒颗粒。这一过程中的一个必需成分是主要衣壳蛋白。在本研究中，我们描述了同多聚体主要和次要衣壳蛋白的特性，包括相应基因的序列。发现次要衣壳蛋白含有一个短的胶原样区域（Gly-X-Y）6。这是首次报道该基序存在于原核生物蛋白中。