Assiri Abdullah S
Department of Cardiology, College of Medicine, King Khaled University, Abha, Saudi Arabia.
Sultan Qaboos Univ Med J. 2011 May;11(2):230-5. Epub 2011 May 15.
This study aimed to investigate the clinical and therapeutic profiles of heart failure (HF) cases admitted to Aseer Central Hospital (ACH), Saudi Arabia.
A retrospective cohort of 300 consecutive patients admitted with the diagnosis of HF to ACH from 1 June 2007 to 31 May 2009 were included in the study. Data on demographic variables, aetiologic factors, risk factors, and therapeutic profiles of patients with HF were collected and analysed.
The patients' mean age was 67.4 ± 13.7 years and 68.7% of them were male. The commonest aetiologies for HF were ischaemic heart disease (IHD) and hypertension in 38.3% and 33.3% of patients, respectively. A total of 61.3% of patients were diabetics. Other risk factors for HF included renal failure in 9.7%, atrial fibrillation in 13%, and anaemia in 48.3% of patients. Echocardiography was performed in 98.7% of cases: the average ejection fraction (EF) was 33% ± 17. Angiotensin converting enzyme inhibitors (ACEI) or angiotensin 2 receptor blockers were used in 68.3% of cases, β-blockers in 51.6% of cases and digoxin in 28.3% of cases.
The major causes of HF in our study were IHD and hypertension. Diabetes and anaemia were common risk factors. The cohort constituted an intermediate HF risk group (ejection fraction (EF) 33%). Important therapeutic agents like angiotensin converting enzyme inhibitor I, β-blockers and digoxin were underutilised. Fostering such therapy in practice will lead to a better outcome in the management of HF patients. Anaemia was a significant risk factor in our HF patients and should be managed properly.
本研究旨在调查沙特阿拉伯阿西尔中心医院(ACH)收治的心力衰竭(HF)病例的临床和治疗情况。
本研究纳入了2007年6月1日至2009年5月31日期间连续300例因心力衰竭诊断入住ACH的患者。收集并分析了患者的人口统计学变量、病因因素、危险因素和治疗情况的数据。
患者的平均年龄为67.4±13.7岁,其中68.7%为男性。心力衰竭最常见的病因分别是缺血性心脏病(IHD)和高血压,分别占患者的38.3%和33.3%。共有61.3%的患者患有糖尿病。心力衰竭的其他危险因素包括9.7%的患者患有肾衰竭、13%的患者患有心房颤动以及48.3%的患者患有贫血。98.7%的病例进行了超声心动图检查:平均射血分数(EF)为33%±17。68.3%的病例使用了血管紧张素转换酶抑制剂(ACEI)或血管紧张素2受体阻滞剂,51.6%的病例使用了β受体阻滞剂,28.3%的病例使用了地高辛。
我们研究中心力衰竭的主要原因是IHD和高血压。糖尿病和贫血是常见的危险因素。该队列构成了一个中度心力衰竭风险组(射血分数(EF)为33%)。血管紧张素转换酶抑制剂I、β受体阻滞剂和地高辛等重要治疗药物的使用不足。在实践中推广此类治疗将使心力衰竭患者的管理取得更好的结果。贫血是我们心力衰竭患者中的一个重要危险因素,应妥善处理。