Jawhar Nazar M T
Department of Pathology, Nineveh Medical College, University of Mosul, Iraq.
Sultan Qaboos Univ Med J. 2011 May;11(2):269-72. Epub 2011 May 15.
Visceral leishmaniasis is a disease caused by a haemoflagellate protozoan of the genus Leishmania. It has a wide geographical spread. Classic cases are found primarily in children and present with typical features that include fever, anaemia, hepatosplenomegaly, hypergammaglobulinaemia, and pancytopenia. The diagnosis is usually achieved by bone marrow smears, culture and serology; however, it can manifest itself atypically, mostly in patients infected with HIV and geriatric immunocompetent patients. We report an unusual case of visceral leishmaniasis diagnosed in a 27 year-old HIV-infected male who presented with abdominal discomfort and diarrhoea of four weeks duration associated with nausea and vomiting, but with no typical symptoms or signs of visceral leishmaniasis. The diagnosis was established through the identification of the Leishmania organism in duodenal and colonic biopsies and confirmed by subsequent bone marrow smears.
内脏利什曼病是一种由利什曼原虫属的血鞭毛虫原生动物引起的疾病。它在地理上分布广泛。典型病例主要见于儿童，具有发热、贫血、肝脾肿大、高球蛋白血症和全血细胞减少等典型特征。诊断通常通过骨髓涂片、培养和血清学检查来实现；然而，它可能表现为非典型，主要见于感染艾滋病毒的患者和老年免疫功能正常的患者。我们报告了一例不寻常的内脏利什曼病病例，该病例发生在一名27岁感染艾滋病毒的男性身上，他出现了持续四周的腹部不适和腹泻，并伴有恶心和呕吐，但没有内脏利什曼病的典型症状或体征。通过在十二指肠和结肠活检中鉴定利什曼原虫确诊，并经随后的骨髓涂片证实。
