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[衣原体感染导致不育及感染风险增加的文化与血清学检测诊断]

[Cultural and serologic Chlamydia detection in diagnosis of sterility and increased risk of infection].

作者信息

Degen K W, Distler W, Graf M, Krech T, Rademacher K, Vossel R, Koldovsky U

机构信息

Universitäts-Frauenklinik Düsseldorf.

出版信息

Geburtshilfe Frauenheilkd. 1990 May;50(5):371-4. doi: 10.1055/s-2008-1026264.

Abstract

364 women were studied for the possible role of chlamydia trachomatis infection as a factor related to infertility. C. trachomatis was isolated from the cervix in 20% of our high-risk STD patients and in a much lower proportion in patients with tubal (5%) or unexplained (4%) infertility. IgG-antibodies to C. trachomatis were found in 75% of patients with tubal infertility, in 44% of women without gynaecological diseases and in 87% of the high-risk STD patients. By contrast, the difference was significant in the IgA-antibody tests. 67% of the women with tubal infertility and only 25% of the women with nontubal infertility were positive. From these data it appears, that antecedent infections with C. trachomatis, as measured by antibody prevalence, are an important factor in infertility of tubal origin.

摘要

对364名女性进行了研究,以探讨沙眼衣原体感染作为与不孕相关因素的可能作用。在我们的高危性传播疾病患者中,20%的人宫颈分离出沙眼衣原体,而在输卵管性不孕(5%)或不明原因不孕(4%)患者中的比例要低得多。75%的输卵管性不孕患者、44%无妇科疾病的女性以及87%的高危性传播疾病患者体内发现了抗沙眼衣原体IgG抗体。相比之下,IgA抗体检测的差异具有显著性。67%的输卵管性不孕女性呈阳性,而非输卵管性不孕女性中只有25%呈阳性。从这些数据来看,通过抗体流行率衡量,既往沙眼衣原体感染是输卵管性不孕的一个重要因素。

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