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路邓葡萄球菌:你不想忽视的凝固酶阴性葡萄球菌。

Staphylococcus lugdunensis: the coagulase-negative staphylococcus you don't want to ignore.

机构信息

Department of Surgery, Division of Critical Care Medicine, The Mount Sinai School of Medicine, New York, NY 10029, USA.

出版信息

Expert Rev Anti Infect Ther. 2011 Oct;9(10):901-7. doi: 10.1586/eri.11.110.

DOI:10.1586/eri.11.110
PMID:21973302
Abstract

Staphylococcus lugdunensis is a virulent coagulase-negative staphylococcus (CoNS) that behaves like Staphylococcus aureus. Toxic shock syndrome, osteomyelitis, septic arthritis and postoperative endopthalmitis have been observed. Endocarditis complicated by heart failure, periannular abscess formation and embolic phenomenon have brought particular attention to this CoNS. Mortality rates for endocarditis appear higher when compared with other CoNS. Owing to the laboratory methods used, identification may be misleading. β-lactam antimicrobials are recommended pending sensitivities. Evaluation for endocarditis should be pursued in bacteremic patients due to its pathogenic potential.

摘要

路邓葡萄球菌是一种毒力较强的凝固酶阴性葡萄球菌(CoNS),其行为类似于金黄色葡萄球菌。已观察到中毒性休克综合征、骨髓炎、化脓性关节炎和术后眼内炎。伴有心力衰竭的心内膜炎、环形脓肿形成和栓塞现象引起了人们对这种 CoNS 的特别关注。与其他 CoNS 相比,心内膜炎的死亡率似乎更高。由于所用的实验室方法,鉴定可能会产生误导。建议在药敏结果出来之前使用β-内酰胺类抗菌药物。由于其致病性,应对菌血症患者进行心内膜炎评估。

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